Sentinel-Node-Biopsie

Bembenek, A.; Gretschel, Stephan; Ulmer, C.; Bayraktar, Soley; Schlag, Peter M.

doi:10.1007/s00761-003-0524-z

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…Neuere Tracer wie Fluoreszin oder Dextrane sind noch in der Erprobung. Bis jetzt gibt es noch keine eindeutigen Untersuchungsergebnisse zur Tracerwahl, somit sind auch keine differenzierten Aussagen zur Wertigkeit der Tracer bei den verschiedenen Tumorentitä-ten möglich [2].…”

Section: Sentinel Lymph Node · Lymphadenectomy · Gastrointestinal Cancerunclassified

Zur Methodik des Sentinel Lymph Node Mapping

Kitagawa

Burian

Kitajima

2004

Chirurg

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Sentinel lymph node mapping is used as a diagnostic method in order to increase staging accuracy without the well-known morbidities of radical lymphadenectomy. The sentinel node is defined as the first node to receive lymphatic drainage from a primary tumor. The sentinel node concept postulates that if the first draining node is negative for metastasis, the remaining lymph nodes in the nodal basin can be spared. Thus one can predict the status of the nodal basin with high accuracy. It also shows that lymphatic spread seems to follow certain rules that do not concern the whole lymphatic basin. Skip metastases were proven to be rare in breast and gastric cancer. The main issue in sentinel lymph node mapping remains the improvement of staging accuracy for detection of lymph nodes most likely to develop metastasis as well as reducing morbidity by planning lymphadenectomies individually for each tumor and each patient.

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Section: Sentinel Lymph Node · Lymphadenectomy · Gastrointestinal Cancerunclassified

Zur Methodik des Sentinel Lymph Node Mapping

Kitagawa

Burian

Kitajima

2004

Chirurg

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Sentinel Lymph Node Mapping

Burian¹,

Sendler²,

Stein³

et al.

Praxis Der Viszeralchirurgie

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Sentinel lymph node in colorectal cancer — 5 years follow up

et al. 2011

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AbstractTo assess the impact of micrometastases in sentinel and non-sentinel lymph nodes on long-term survival rates of patients treated for colorectal cancer (CRC). Data of 57 patients diagnosed with CRC and treated in the Department of Surgical Oncology in Gdansk in the years 2002–2006 were retrospectively analyzed. Clinico-histopathological data were analyzed using chi-square tests. The effect on long-time survival rates was analyzed using Kaplan-Meier survival probability estimates. Identification of the SLN was performed using the blue dye staining method. All regional lymph nodes were subject to standard histopathological examination. Additionally in 32(56.14%) patients whose nodes were found negative for metastases on standard staining further immunohistochemical analyses were performed. In the analyzed group SLNB was performed in 42(73.7%) patients with colon cancer and in 15(26.3%) with rectal cancer. Identification of the SLN was possible in 45(78.9%) patients. The sensitivity of SLNB was 33%. False negatives were found in 66%. SLNB is a feasible method in CRC patients. We presume that lack of micrometastases in the SLN and non-SLN cannot be regarded as a prognostic factor.

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Sentinel-Node-Biopsie

Cited by 3 publications

References 23 publications

Zur Methodik des Sentinel Lymph Node Mapping

Zur Methodik des Sentinel Lymph Node Mapping

Sentinel Lymph Node Mapping

Sentinel lymph node in colorectal cancer — 5 years follow up

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