Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions. Certain anticonvulsants, immuno-suppressive drugs and a number of calcium channel blockers have been shown to produce similar gingival overgrowths in certain susceptible patients. Amlodipine is a comparatively new calcium channel blocker and has been used with increasing frequency in the management of hypertension and angina. Although amlodipine is considered as a safe drug, very rarely it may induce gingival overgrowth also. A rare case of amlodipine-induced gingival overgrowth has been reported herein in a 50-year-old female patient. The treatment aspect included Phase-1 therapy, substitution of the drug, the surgical excision and the maintenance and supportive therapy resulting in excellent clinical outcome.
Objectives:The purpose of the present study was to evaluate and compare the relationship between the levels of hepatocyte growth factor (HGF) in gingival crevicular fluid (GCF) and saliva, both clinically and biochemically, in patients with and without chronic periodontitis.Materials and Methods:For this study, 36 patients (12 male, 24 female) were selected in the age range of 18-60 years (mean, 32.7±11.1 years). The subjects were assigned to three groups, which included Group I (control), Group II (chronic periodontitis with probing depth PD <5 mm), and Group III (chronic periodontitis with PD ≥5 mm). Clinical parameters included plaque index, gingival index, sulcus bleeding index, PD, and clinical attachment level. The GCF samples were taken by using the capillary tubes whereas saliva was collected by the suction method. The levels of HGF in GCF and in saliva were estimated using an enzyme linked immunosorbant assay reader.Results:There was a significant correlation in the levels of HGF in GCF and in saliva of patients with and without chronic periodontitis. The results also indicated that the HGF levels in GCF and saliva correlated well with the clinical parameters and with the severity of the periodontal disease.Conclusion:Both GCF and saliva can be used to estimate the levels of HGF and thus may be regarded as a novel marker for periodontal disease activity.
Introduction:The periodontium has its own adaptive capacity to the forces exerted on the teeth, this varies in different persons and in the same persons at different times. In current practise, the occlusal factors acting on the tooth are examined by articulation paper marks, waxes, pressure indicator paste, etc. However, the drawbacks of these methods are that they do not detect simultaneous contact nor do they quantify time and force. This study was conducted to determine and to analyse the distribution of occlusal loading forces, occlusal contact variability and its correction in the management of periodontitis using T-Scan III™.Methods: A total of ten chronic periodontitis patients were selected for the study. Scaling and root planing procedure and occlusal analysis using T-Scan III™ were performed on them. The amount of occlusal forces was found to be highly concentrated either on the right or the left side of the dental arches. Thus, the occlusal adjustments were carried out to minimize and dissipate the abnormal occlusal forces.Result: T-Scan analysis was repeated to analyse for the distribution of occlusal forces which depicted a reduction in the amount of occlusal forces and these forces were distributed nearly equally on the dental arch.
Conclusion:Comparing and analysing the occlusal distribution of forces prior to and after the occlusal adjustments using T-Scan III™ system showed equilibrium in occlusal force distribution.
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