The topological analysis of chiral molecular models has provided the framework of a general system for the specification of their chirality. The application, made in and bejore 19S6, of this system to organic-chemical configurations is generally retained, but is redefined with respect to certain types of structure, largely in the light of experience gained since 1956 in the Beilstein Institute and elsewhere. The system is now extended to deal, on the one hand, with organic-chemical conformations, and, on the other, with inorganicchemical configurations to ligancy six. Matters arising in connexion with the transference of chiral specijications from model to name are considered, notably that of the symbiosis in nomenclature of expressions of the general system and of systems of confined scope.
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