Objective: To investigate the dietary pattern and nutritional status of adolescent girls attending schools in Dhaka city and to examine the association with various social factors. Design: Cross-sectional study. Setting: Girls high schools in Dhaka city. Subjects: A total of 384 girls, aged from 10 to 16 years, who were students of classes VI to IX of 12 girls high schools in Dhaka city were selected by systematic random sampling. Nutrient intake was assessed using the 24-h recall method and the usual pattern of food intake was examined using a 7-day food frequency questionnaire. Results: The prevalence of undernutrition among the participants assessed as stunting was 10% overall with younger girls being less stunted (2%) than older girls (16%), whereas 16% were thin with relatively more of the younger girls (21%) being thin than of the older girls (1Ph). Based on the usual pattern of food intake, a substantial proportion of the girls did not consume eggs (26%), milk (35%) or dark green leafy vegetables (20%). By comparison, larger proportions consumed meat (50%) and fish (65%) at least four times a week. For the intake of energy and protein, only 9 and 17% of the girls, respectively, met the recommended daily allowance (RDA). For nearly 77% of the girls, the intake of fat was less than the recommendation. Intakes less than the RDA were found for iron (77% of the girls), calcium (79%), vitamin A (62%), vitamin C (67%), and riboflavin (96%). Based on the food consumption data, cereals were the major source of energy (57%), thiamin (67%), niacin (63%) and iron (37%).Animal sources supplied 50% of dietary protein. Cooking fats were the principal source of fat (67%) in the diet. Milk was the major contributor for riboflavin and preformed vitamin A (retinol). Leafy vegetables and fruits were the main sources of provitamin A (carotenes). The girls from families with less educated parents were more likely to be thin and short for their age. Those girls from families with lower incomes and less educated parents had a dietary pattern which tended to be poor with regard to egg, milk, meat and fruit, with lower intakes of protein, fat and riboflavin. Conclusion:The findings indicate that the diets of these girls tended to be inadequate both for macronutrients and micronutrients, with significant health implications. There was also a relationship between the family income and the education of the parents with the nutritional status of the girls.We are interested in the factors which promote good fetal growth. It is clear that the nutrition of the mother before and around the time of conception is of great importance', hence we are especially interested in

Twice-weekly MMN supplementation for 12 wk significantly improved the status of the micronutrients assessed but was not more efficacious than was supplementation with iron and folic acid alone in improving the hematologic status of anemic adolescent girls. More frequent doses may be needed to achieve full benefit.

Objective: To investigate the prevalence of selected micronutrient deficiencies amongst anaemic adolescent schoolgirls in rural Bangladesh and to examine their relationship with haemoglobin (Hb) levels. Design: A cross-sectional study. Setting: Girls' high schools in rural areas of Dhaka District in Bangladesh. Subjects and methods: Three hundred and ten anaemic adolescent girls aged 14-18 years from eight schools participated in the study. Information on personal characteristics and food habits were collected by interview. Parents were asked about their socio-economic conditions. Anthropometric data and blood samples were collected following the interview. Results: Twenty-eight per cent of the girls had depleted iron stores (serum ferritin o12.0 mg/l), 25% had folic acid deficiency (red blood cell folic acid o317 nmol/l), 89% had vitamin B 2 (erythrocyte glutathione reductase activity coefficient X1.4) and 7% had vitamin B 12 deficiencies (serum vitamin B 12 o150 pmol/l). Although the prevalence of vitamins A and C deficiency was very low, a significant proportion had low vitamin A (serum retinol between 0.70 and o1.05 mmol/l) and vitamin C status (plasma ascorbic acid between 11.4-23.0 mmol/l). Frequency of consumption of meat, serum ferritin and vitamin B 2 status were found to be strongly related to Hb by multiple regression analysis. For 1 mg/l change in serum ferritin, there was a 0.13 g/l change in Hb when adjusted for other factors. Conclusions: There is coexistence of micronutrient deficiencies among anaemic adolescent girls in rural Bangladesh, although they do not suffer from energy deficiency. Of all micronutrients, only iron and vitamin B 2 concentrations were found to be related to the Hb concentration.

Previous short-term supplementation studies showed no additional hematologic benefit of multiple micronutrients (MMN) compared with iron + folic acid (IFA) in adolescent girls. This study examines whether long-term once- or twice-weekly supplementation of MMN can improve hemoglobin (Hb) and micronutrient status more than twice-weekly IFA supplementation in anemic adolescent girls in Bangladesh. Anemic girls (n = 324) aged 11-17 y attending rural schools were given once- or twice-weekly MMN or twice-weekly IFA, containing 60 mg iron/dose in both supplements, for 52 wk in a randomized double-blind trial. Blood samples were collected at baseline and 26 and 52 wk. Intent to treat analysis showed no significant difference in the Hb concentration between treatments at either 26 or 52 wk. However, after excluding girls with hemoglobinopathy and adjustment for baseline Hb, a greater increase in Hb was observed with twice-weekly MMN at 26 wk (P = 0.045). Although all 3 treatments effectively reduced iron deficiency, once-weekly MMN produced significantly lower serum ferritin concentrations than the other treatments at both 26 and 52 wk. Both once- and twice-weekly MMN significantly improved riboflavin, vitamin A, and vitamin C status compared with IFA. Overall, once-weekly MMN was less efficacious than twice-weekly MMN in improving iron, riboflavin, RBC folic acid, and vitamin A levels. Micronutrient supplementation beyond 26 wk was likely important in sustaining improved micronutrient status. These findings highlight the potential usefulness of MMN intervention in this population and have implications for programming.

The results of the present study implies that the analyzed plants possess varying degree of antioxidant capacity and, therefore, the antioxidant potency of these underused plants may be utilized to prevent oxidative damage and oxidative stress related disorders.

Objective: To investigate the prevalence of vitamin A deficiency (VAD) among pregnant women in rural Bangladesh, and examine the relationship between various factors and vitamin A status. Setting: Community Nutrition Promoter (CNP) centres in Kapasia sub-district of Gazipur district, Bangladesh. Design: A cross-sectional study. Subjects and methods: Two hundred women, aged 18-39 years, in their second or third trimester of pregnancy were selected from seventeen CNP centres in four unions of Kapasia sub-district where they usually visit for antenatal care. Various socio-economic, personal and pregnancy-related information, dietary intake of vitamin A and mid-upper arm circumference (MUAC) data were collected. Serum retinol (vitamin A) concentration was determined. Results: More than half (51 %) of the pregnant women had low vitamin A status (serum retinol ,1?05 mmol/l) with 18?5 % having VAD (serum retinol ,0?70 mmol/l). Fifty-three per cent of the women's vitamin A intake was less than the recommended dietary allowance. By multiple regression analysis, MUAC, per-capita expenditure on food and wealth index were found to have significant independent positive relationship with serum retinol concentration, while gestational age of the pregnant women had a negative relationship. The overall F-ratio (10?3) was highly significant (P 5 0?0001), the adjusted R 2 was 0?18 (multiple R 5 0?45).

Concentrations of fourteen trace elements (Cd, As, Pb, Cr, Ni, Zn, Se, Cu, Mo, Mn, Sb, Ba, V and Ag) in the composite samples of most frequently consumed two staple foods, i.e. rice and wheat (collected from 30 different agroecological zones for the first time in Bangladesh) were measured by ICP-MS. The mean concentrations (mg/kg fresh weight) of Cd, As, Pb, Cr, Ni, Zn, Se, Cu, Mo, Mn, Sb, Ba, V and Ag were found as 0.088, 0.321, 0.713, 0.183, 0.213, 13.178, 0.0256, 1.985, 0.102, 4.654, 0.0033, 0.144, 0.081 and 0.007 and 0.011, 0.281, 0.221, 0.352, 0.145, 15.472, 0.245, 1.894, 0.209, 22.077, 0.0012, 3.712, 0.023 and 0.0013 in rice and wheat samples, respectively. Dietary risk of human health (non-carcinogenic and carcinogenic risks) was assessed by USEPA deterministic approaches. Total target hazard quotient (THQ) values for As and Pb were higher than 1, suggesting that people would experience significant health risks from consuming rice and wheat. However, the THQ of other metals were all less than 1. Also, the estimation showed that the target carcinogenic risk (TR) of As and Pb exceeded the accepted risk level of 1 × 10(-6). Moreover, concerning the nutritional requirements of essential elements for a sound health, the recommended doses for the daily intake of Mn was conveniently supplied by the studied cereals; however, Cr, Zn, Se, Cu and Mo were below the recommend daily allowances (RDAs). Thus, the carcinogenic and non-carcinogenic risk of As and Pb with lower supplementation of essential elements via staple foods for Bangladeshi people is a matter of concern.

The present study examined whether long-term supplementation with once-and twice-weekly multiple micronutrients (MMN-1 and MMN-2) can improve Hb and micronutrient status more than twice-weekly Fe-folic acid (IFA-2) supplementation in non-anaemic adolescent girls in Bangladesh. An equal number of 324 rural schoolgirls aged 11-17 years were given MMN-1 or MMN-2 or IFA-2 supplements for 52 weeks in a randomised, double-blind trial. Blood samples were collected at baseline, and at 26 and 52 weeks of supplementation. The girls receiving IFA-2 supplements were more likely to be anaemic than the girls receiving MMN-2 supplements for 26 weeks (OR 5·1, 95 % CI 1·3, 19·5; P¼ 0·018). All three supplements reduced Fe deficiency effectively. Both the MMN-1 and MMN-2 groups showed significantly greater improvements in vitamins A, B 2 and C status than the girls in the IFA-2 group, as might be expected. Receiving a MMN-1 supplement was found to be less effective than MMN-2 supplement in improving Fe, vitamins A, B 2 and folic acid status. Receiving micronutrient supplements beyond 26 weeks showed little additional benefit in improving micronutrient status. In conclusion, given twice-weekly for 26 weeks, MMN supplements can improve micronutrient status effectively with no significant increase in Hb concentration compared with IFA supplements in non-anaemic Bangladeshi adolescent girls. However, it significantly reduces the risk of anaemia. Before any recommendations can be made, further research, including into cost-effectiveness, is needed to see whether MMN supplementation has any additional longer-term health benefits over that of IFA supplementation in this population.