ÖzetAmaç: Primer aç›k aç›l› glokomlu olgularda Optik Koherens Tomografi (OKT) ile ölçülen retina sinir lifi tabakas› ve gangliyon hücre kompleksinin kal›nl›klar›n›n normal olgular ile karfl›laflt›r›lmas›. Gereç ve Yöntem: Çal›flmaya 86's› glokom 51'i normal olmak üzere 137 olgunun 274 gözü al›nd›. OKT ile retina sinir lifi tabakas› (RSLT) ve gangliyon hücre kompleksi (GHK) ölçümleri yap›ld›. Her göz için RSLT ve GHK ortalama de¤eri, alt ve üst yar›lar›n ölçümü ile ölçüm s›ras›nda alet taraf›ndan verilen Sinyal gücü göstergesi (SGG) sonuçlar› kaydedildi. Sonuçlar, glokom hastalar›n›n kendi aralar›nda korelasyonu ve kontrol grubu ile karfl›laflt›r›lmas› aç›s›ndan istatistiksel olarak de¤erlendirildi. Sonuçlar: Her iki olgu grubu aras›nda yafl ve cinsiyet oranlar› aç›s›ndan anlaml› fark bulunmad›. RSLT ve GHK ortalama de¤erleri glokomlu ve normal olgularda s›ras›yla 97,03±13,85 μm, 113,48±9,00 μm; üst yar› ölçümleri yine s›ras›yla 95,83±13,71 μm, 111,49±11,14 μm; alt yar› ölçümleri ise 98,44±15,63 μm, 115,50±9,25 Ìm olarak saptand›. Tüm de¤erler glokom olgular›nda kontrol grubuna göre istatiksel olarak anlaml› düzeyde düflük bulundu. SGG sonuçlar› de¤erlendirildi¤inde ise yine glokom olgular›nda kontrol grubuna göre istatiksel olarak anlaml› düzeyde düflük bulundu. RSLT SGG sonuçlar›, GHK SGG sonuçlar› ile karfl›laflt›r›ld›¤›nda ise RSLT sonuçlar› GHK sonuçlar›na göre istatiksel olarak anlaml› düzeyde düflük bulundu. Tart›flma: Glokom hastalar›n›n tan› ve izleminde RSLT kadar GHK ölçümünün de önemli oldu¤u dikkat çekici olmufltur. (Turk J Ophthalmol 2010; 40: 338-42) Anahtar Kelimeler: Glokom, optik koherens tomografi, retina sinir lifi tabakas›, ganglion hücre kompleksi Summary Purpose: To compare the optical coherence tomography (OCT) measurements of retinal nerve fiber layer (RNFL) and ganglion cells complex (GCC) thickness in primary open-angle glaucoma patients and normal patients. Material and Method: 274 eyes of 137 subjects were enrolled in the study: 86 glaucoma patients and 51 normal subjects as a control group. RNFL and GCC were measured by OCT. The average values of GCC and RNFL for each eye, the superior and inferior half measurements and the signal strength indicator (SSI) results were recorded. Results were statistically evaluated by correlation among the glaucoma patients and comparison between the normal and glaucoma groups. Results: There was no significant difference between the groups for age and gender distributions. The mean RNFL and GCC measurements were 97.03±13.85 μm in glaucoma patients and 113.48±9.00 μm in normal subjects. Superior half measurements were 95.83±13.71 μm in glaucoma patients and 111.49±11.14 μm in normal subjects. Inferior half measurements were 98.44±15.63 μm in glaucoma patients and 115.50±9.25 μm in normal subjects. Both GCC and RNFL averages and superior and inferior measurements were found statistically significantly lower in glaucoma group. SSI results were also statistically significantly lower in the glaucoma group. SSI of RNFL results were statistically significant...
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