Health literacy, a more complex concept than knowledge, is a required capacity to obtain, understand, integrate and act on health information [1], in order to enhance individual and community health, which is defined by different levels, according to the autonomy and personal capacitation in decision making [2]. Medium levels of Health literacy in an adolescent population were found in a study conducted in 2013/2014, being higher in sexual and reproductive health and lower in substance use. It was also noticed that the higher levels of health literacy were in the area adolescents refer to have receipt more health information. The health literacy competence with higher scores was communication skills, and the lower scores were in the capacity to analyze factors that influence health. Higher levels were also found in younger teenagers, but in a higher school level, confirming the importance of health education in these age and development stage. Adolescents seek more information in health professionals and parents, being friends more valued as a source information in older adolescents, which enhance the importance of peer education mainly in older adolescents [3]. As a set of competences based on knowledge, health literacy should be developed through education interventions, encompassing the cultural and social context of individuals, since the society, culture and education system where the individual is inserted can define the way the development and enforcement of the health literacy competences [4]. The valued sources of information should be taken into account, as well as needs of information in some topics referred by adolescents in an efficient health education. Schizophrenia is a serious and chronic mental illness which has a profound effect on the health and well-being related with the well-known nature of psychotic symptoms. The exercise has the potential to improve the life of people with schizophrenia improving physical health and alleviating psychiatric symptoms. However, most people with schizophrenia remains sedentary and lack of access to exercise programs are barriers to achieve health benefits. The aim of this study is to evaluate the effect of exercise on I) the type of intervention in mental health, II) in salivary levels of alpha-amylase and cortisol and serum levels of S100B and BDNF, and on III) the quality of life and selfperception of the physical domain of people with schizophrenia. The sample consisted of 31 females in long-term institutions in the Casa de Saúde Rainha Santa Isabel, with age between 25 and 63, and with diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). Physical fitness was assessed by the six-minute walk distance test (6MWD). Biological variables were determined by ELISA (Enzyme-Linked Immunosorbent Assay). Psychological variables were assessed using SF-36, PSPP-SCV, RSES and SWLS tests. Walking exercise has a positive impact on physical fitness (6MWD -p = 0.001) and physical components of the psychological test...

Objetivo: conhecer a perspectiva dos profissionais de saúde sobre a cultura de segurança do paciente. Método: trata-se de estudo quantitativo, descritivo, observacional, com 242 profissionais da saúde. Coletaram-se os dados de por meio de um questionário, tabulando-se pelos softwares: SPSS V20, Minitab 16 e Excel Office 2010. Confeccionaram-se tabelas para apresentar os resultados realizando-se a análise descritiva. Resultados: revela-se que, dos respondentes, 50,4% foram capacitados nos últimos dez anos, 90,1% afirmaram a cultura de segurança como preocupação mundial, 72,3% conheciam os protocolos e os praticavam, 74,7% acreditavam que a cultura de segurança evita erros, 97,0% afirmaram a importância do envolvimento de todos para a mudança da cultura. Conclusão: observou-se inconstância na perspectiva dos profissionais em relação ao entendimento sobre a cultura de segurança e, entre outras dificuldades, a falta de capacitação, de entrosamento no trabalho em equipe, de comprometimento com as práticas diárias e de disseminação da cultura em todo o hospital. Descritores: Cultura; Segurança do Paciente; Opinião Pública; Pessoal de Saúde; Hospitais; Assistência à Saúde. ABSTRACTObjective: to know the perspective of health professionals about the culture of patient safety. Method: this is a quantitative, descriptive, observational study with 242 health professionals. Data was collected by means of a questionnaire, tabulated by the software: SPSS V20, Minitab 16 and Excel Office 2010. Tables were made to present the results by performing the descriptive analysis. Results: it appears that 50.4% of the respondents were trained in the last ten years, 90.1% affirmed the safety culture as a worldwide concern, 72.3% knew the protocols and practiced them, 74.7% believed that safety culture avoids mistakes, 97.0% affirmed the importance of everyone's involvement for culture change. Conclusion: there was inconsistency in the perspective of professionals regarding the understanding of the safety culture and, among other difficulties, lack of training, team work, commitment to daily practices and dissemination of culture throughout the hospital. Descriptors: Culture; Patient Safety; Public Opinion; Health Personnel; Hospitals; Health Care.RESUMENObjetivo: conocer la perspectiva de los profesionales de la salud sobre la cultura de seguridad del paciente. Método: este es un estudio cuantitativo, descriptivo, observacional con 242 profesionales de la salud. Los datos se recopilaron mediante un cuestionario tabulado por los softwares: SPSS V20, Minitab 16 y Excel Office 2010. Se realizaron tablas para presentar los resultados mediante el análisis descriptivo. Resultados: parece que el 50.4% de los encuestados fueron capacitados en los últimos diez años, el 90.1% afirmó que la cultura de seguridad era una preocupación mundial, el 72.3% conocía los protocolos y los practicaba, el 74.7% creía que la cultura de seguridad evita errores, el 97.0% afirmó la importancia de la participación de todos para el cambio cultural. Conclusión: hubo inconsistencia en la perspectiva de los profesionales con respecto a la comprensión de la cultura de seguridad y, entre otras dificultades, la falta de capacitación, buen convivio en el trabajo en equipo, el compromiso con las prácticas diarias y difusión de la cultura en todas partes del hospital. Descriptores: La Cultura; Seguridad del Paciente; Opinión Pública; Personal de Salud; Los Hospitales; Asistencia a la Salud.

12.90 to 13.09 million VND when calculating 100% of T-IV wastes. For the entire course of treatment, T-SC economises from 45.11 to 232.16 million VND in early stage and from 25.52 to 91.65 million VND in metastasis stage depending on the percentage of wastage. In the minimized cost components, drug cost accounts for the highest proportion, fluctuating from 70.52% to 94.27% based on stage and portion of wastage. Other cost components are insignificant and do not change the value in all cases. Conclusions: T-SC is more economical than T-IV in treatment of HER2+ breast cancer in both cases of early and metastasis stage. In particular, drug cost is the most economical.

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