Magnesium pemoline, a central nervous stimulant which may affect brain RNA production, produces a deficit in passive avoidance behavior. The main effect of the drug appears to be stimulation, with no effect on learning.

No abstract

Magnesium pemoline, a central nervous stimulant implicated in brain RNA production, decreases both time and errors in the Hebb-Williams maze, a test of animal intelligence. The effect of the drug on errors is confounded with its effect on time, but seems to have a component independent of the latter effect.