Chamber angle tissue from human eyes was investigated with scanning electron microscopy. The uveal and corneoscleral parts of the trabecular meshwork are described. The endothelial cells of the inner wall of Schlemm's canal arc long and slender and, at most places, are oriented along the lumen of the canal. The average projected surface of a cell towards the canal is about 480 pm2. The total number of endothelial cells in the inner wall of the canal is about 23,000. The cells have pores with diameters up to 3(5) ,um. The total number of pores is about 20,000. Calculations show that if all the observed pores exist in vivo, the resistance t o outflow in the paths through the endothelial cells is a small fraction of the total resistance to outflow.

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