A system for passive implantable pressure sensors

Rosengren, Lars; Rangsten, Pelle; Bäcklund, Ylva; Hök, Bertil; Svedbergh, Björn; Selén, Göran

doi:10.1016/0924-4247(93)00664-p

Cited by 42 publications

(21 citation statements)

References 3 publications

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“…We first describe a size scaling path to achieve the smallest passive sensors reported for wireless pressure monitoring, with dimensions of 1 Â 1 Â 0.1 mm 3 . At a volume of 0.1 mm 3 , this is more than an order of magnitude smaller than previously reported research devices [22][23][24][25][26] and more than two orders smaller than commercial solutions [15][16][17][18] . We apply this system to capturing human radial pulse waveforms in real-time with externally placed wireless sensors.…”

mentioning

confidence: 70%

“…These devices are more than an order of magnitude smaller in volume than recent research devices for intraocular pressure sensing [22][23][24][25][26] and more than two orders smaller than commercial solutions [15][16][17][18] . We are able to achieve this level of scaling by leveraging the presented GDD detection scheme, which overcomes the operating frequency limits of traditional strategies and exhibits insensitivity to lossy tissue environments.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, microfabrication techniques and microelectromechanical system technology have been applied to reduce device footprints in passive wireless sensing of intraocular pressures [18][19][20][21][22] . However, with all the sensors operating below a few hundred MHz, none has been able to miniaturize below a few mm 3 in volume [3][4][5][6][7][8][9][10][22][23][24][25][26] . Traditional passive strategies have been inherently limited by the self-resonant frequency of readout circuitry because interference effects make it difficult to detect sensors operating near and above this frequency [27][28][29] .…”

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confidence: 99%

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Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care

et al. 2014

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Continuous monitoring of internal physiological parameters is essential for critical care patients, but currently can only be practically achieved via tethered solutions. Here we report a wireless, real-time pressure monitoring system with passive, flexible, millimetre-scale sensors, scaled down to unprecedented dimensions of 1 Â 1 Â 0.1 cubic millimeters. This level of dimensional scaling is enabled by novel sensor design and detection schemes, which overcome the operating frequency limits of traditional strategies and exhibit insensitivity to lossy tissue environments. We demonstrate the use of this system to capture human pulse waveforms wirelessly in real time as well as to monitor in vivo intracranial pressure continuously in proof-of-concept mice studies using sensors down to 2.5 Â 2.5 Â 0.1 cubic millimeters. We further introduce printable wireless sensor arrays and show their use in real-time spatial pressure mapping. Looking forward, this technology has broader applications in continuous wireless monitoring of multiple physiological parameters for biomedical research and patient care.

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confidence: 70%

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care

et al. 2014

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“…Having characteristic dimensions at the microscale, MEMS devices/systems are highly suitable for implantable applications, particularly for implantable IOP sensors. Many telemetric MEMS pressure sensors, using passive or active measurement modalities, have been developed to realize continuous IOP monitoring directly from inside the eye with accurate and precise pressure readouts [4][5][6][7][8]. However, the sensors will eventually be implanted inside the eye and exposed to the in vivo environment such that power consumption would be a concern in the use of the active sensors.…”

Section: Introductionmentioning

confidence: 99%

Implantable micromechanical parylene-based pressure sensors for unpowered intraocular pressure sensing

Chen

Rodger

Agrawal

et al. 2007

J. Micromech. Microeng.

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This paper presents the first implantable, unpowered, parylene-based microelectromechanical system (MEMS) pressure sensor for intraocular pressure (IOP) sensing. From in situ mechanical deformation of the compliant spiral-tube structures, this sensor registers pressure variations without electrical or powered signal transduction of any kind. Micromachined high-aspect-ratio polymeric hollow tubes with different geometric layouts are implemented to obtain high-sensitivity pressure responses. An integrated device packaging method has been developed toward enabling minimally invasive suture-less needle-based implantation of the device. Both in vitro and ex vivo device characterizations have successfully demonstrated mmHg resolution of the pressure responses. In vivo animal experiments have also been conducted to verify the biocompatibility and functionality of the implant fixation method inside the eye. Using the proposed implantation scheme, the pressure response of the implant can be directly observed from outside the eye under visible light, with the goal of realizing convenient, direct and faithful IOP monitoring in glaucoma patients.

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“…In wireless RF active sensing, the power transfer, size, and cost are critical concerns [18,19]; however, the passive sensing approaches have relatively dexterous design considerations [20,21]. A capsulated sensor with an electrical LC tank resonant circuit was implanted to the anterior chamber for pressure monitoring [22,23] transcutaneous, ophthalmic and intracranial pressure monitoring [24][25][26]. Stretchable serpentine design with LC resonators for wireless determination of strain properties of skin surface was reported [27].…”

Section: Introductionmentioning

confidence: 99%

Self-similar design for stretchable wireless LC strain sensors

Huang

Dong

Huang

et al. 2015

Sensors and Actuators A: Physical

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a b s t r a c tStretchable sensors provide a foundation for applications that exceed the scope of conventional device technologies due to their unique capacity to integrate with soft materials and curvilinear surfaces. This article presents the implementation and characterization of a large-area stretchable wireless RF strain sensor, operating at around 760 MHz, based on the concept of self-similar design. It has an electrical LC resonant circuit formed by a self-similar inductor coil and a capacitor to facilitate passive wireless sensor. The inductance of the wireless sensor varies with the elongation of the PDMS substrate, so is the resonance frequency of the sensor that is detected using an external coil linked to a vector network analyzer. Finite element modeling was used in combination with experimental verification to demonstrate that the wireless strain sensor with 300 m width can be stretched up to 40%. Self-similar structured coil incorporating variable inductance has been implemented to monitor the strain of artificial skin. Strain response of the stretchable wireless sensor has been characterized by experiments, and demonstrates high strain responsivity about 33.7 MHz/10%, which confirms the feasibility of strain sensing for biomedical and wearable applications.

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A system for passive implantable pressure sensors

Cited by 42 publications

References 3 publications

Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care

Continuous wireless pressure monitoring and mapping with ultra-small passive sensors for health monitoring and critical care

Implantable micromechanical parylene-based pressure sensors for unpowered intraocular pressure sensing

Self-similar design for stretchable wireless LC strain sensors

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