As statedby theeditorin the preface, the purpose of thistext is to review "issuesin various aspects of antimicrobial resistance thatchallenge our ability to slowits inexorable progress, andhowwe can make the bestuseof theeffectiveness of currently available antimicrobials." Content: Three sectionsof the text focus on specificpathogens,includingcommunity-associated methicillin-resistant Staphylococcus aureus,organisms that produce extended-spectrum~-I actamase, and bacterial pneumonia during influenzapandemics. Four of the sectionsfocus on resistance within the fluoroquinolone, antifungal,anthelmintic, and antiretroviral drug classes.Twoadditional sections focus uponlocationspecific concerns,including boththe outpatient and hospital health-care settings, and I section examines the costimplications associated withantimicrobial resistance. In general,each sectionprovides an overviewof the mechanisms of resistance, highlights the current limitations to pharmacologic treatment of resistant pathogens, reviews strategies for the prevention and controlof the spreadof resistant pathogens, and provides insight intothe future direction of research in theseareas. Usability: Overall, the text is compact, well organized,and easy to read.The text includes an index for easy identification of topics,as well as up-to-date reference lists. Highlights: Due to the multidimensional approach to the information included withineach section,this text would be of particularinterestto practitioners who desireantimicrobial stewardship withintheir practice or institution. Limitations: Because this text does not providea comprehensive review,but insteadprovides an overview of selected resistance issues,it is limitedin scope.Therefore, this text may be of limitedutility, particularly for those desiring an inclusivereview of resistant pathogens.While each section provides the reader witha thorough overview of the topic.a functional knowledge of infectious diseases and associated terminology is required. Comparison to Other Related Books: Other textbooks available on this topic, namely,AntimicrobialResistance:Problem Pathogensand Clinical Countermeasures, and Antimicrobial Drug Resistance (a 2-volume set), providecontent similar to that presented within this text, although it is much further expanded and inclusive of many more pathogens. Additionally, several generalinfectious disease textbooks include information related to antimicrobial resistanceamong additional topics. Reviewer's Summary: As stated withinthe book's text, "Antibiotic resistant bacteriaare a significant problemof public healthimportance, and are responsible for substantial morbidity, mortality, and cost." While• limited in scope,this text provides a multidimensional overview of some of the pressing issues in infectiousdisease today and would serve as a useful toolto thoseinterested inexpanding theirknowledge on thesespecifictopics.
Contemporary Hasidic Yiddish speakers perceive a distinction between “Hungarian” and “Polish” Yiddish. This article explores that distinction by examining the Yiddish of the Bobover Hasidic community, the largest “Polish” Hasidic group in the United States; the Yiddish of its “Hungarian” counterpart, Satmar, and its rootedness in the Unterland Hungarian Yiddish was demonstrated by Krogh (2012), reflecting the origins of the Satmar dynasty. But is Bobover Yiddish similarly rooted in western Galician Yiddish? Interviews with informants from the Bobover community reveal a mixed picture. All showed phonological features of non-Hungarian Central Yiddish, but all featured “Hungarian” vocabulary. While most of the informants’ grandparents were from interwar Poland, several had grandparents from the Unterland region; one-third identified their spouses as “Hungarian” or were members of “Hungarian” Hasidic communities. This shows the permeability of the two groups, leading to a mixing of features, which creates the need for shibboleths as clear markers of identity.
The author suggests that a new paradigm may be needed which holds that some suicides may be inevitable. The goal of this paradigm would be to diminish the sense of failure and inadequacy felt by many psychiatrists who experience the suicide of a patient and to increase understanding of the unique biopsychosocial profile of those whose suicides appear to be inevitable. The author stresses that this proposed paradigm should not be misconstrued as therapeutic nihilism but rather should serve to stimulate efforts to treat this patient population more effectively. Risk factors that place individuals at high risk for suicide are reviewed, including presence of a mental illness, genetic predisposition, and factors such as a history of abuse, divorce, unemployment, male gender, recent discharge from a psychiatric hospital, prior suicide attempts, alcohol or other substance abuse, a history of panic attacks, and persistent suicidal thoughts, especially if coupled with a plan. The author notes that, in those suicides that appear to have been inevitable, risk factors are not only numerous but at the extreme end of profound pathology. The example of Ernest Hemingway is used to illustrate how such a combination of risk factors may have contributed to his eventual suicide. Psychiatrists, like other doctors, may have to acknowledge that some psychiatric disorders are associated with a high mortality rate as a natural outcome. This could lead to heightened vigilance, a more realistic view of what can and cannot be achieved with therapy, and efforts to improve the quality of life of patients at high risk for suicide with the goal of reducing this risk and prolonging their lives. (Journal of Psychiatric Practice 2012;18:221-224).
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