Synopsis of Psychiatry

Kaplan, Harold; Sadock, Benjamin J.

doi:10.1097/00004850-198904000-00007

Cited by 118 publications

(168 citation statements)

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“…9 The age of criteria onset being significantly different for males and females in this study corresponds to previous findings that the peak ages of onset are 15 to 25 years for men and 25 to 35 years for women. 10 The results indicating a strong association between the use of cannabis and age at onset of psychosis in male schizophrenia patients match those of a study in Dutch male schizophrenia patients. 9 Early deviant behaviour emerged as the most important factor in determining age of criteria onset in the present study, with the early deviant behaviour group having the oldest age of onset and the more severe group the youngest.…”

Section: Discussionsupporting

confidence: 75%

Cannabis and other variables affecting age at onset in a schizophrenia founder population

et al. 2006

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Section: Discussionsupporting

confidence: 75%

Cannabis and other variables affecting age at onset in a schizophrenia founder population

et al. 2006

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“…Among US adults over age 65, prevalence estimates of dementia range from 5 to 15%, with Alzheimer's Disease (AD) being the most common type of dementia (Kaplan and Sadock, 1998;Evans et al, 1989;Losonczy et al, 1998). A recent review estimated that worldwide 24 million people have dementia, and that this number will double by the year 2020 (Ferri et al, 2005).…”

mentioning

confidence: 99%

ACNP White Paper: Update on Use of Antipsychotic Drugs in Elderly Persons with Dementia

Jeste

Blazer

Casey

et al. 2007

Neuropsychopharmacol

325

273

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In elderly persons, antipsychotic drugs are clinically prescribed off-label for a number of disorders outside of their Food and Drug Administration (FDA)-approved indications (schizophrenia and bipolar disorder). The largest number of antipsychotic prescriptions in older adults is for behavioral disturbances associated with dementia. In April 2005, the FDA, based on a meta-analysis of 17 double-blind randomized placebo-controlled trials among elderly people with dementia, determined that atypical antipsychotics were associated with a significantly (1.6-1.7 times) greater mortality risk compared with placebo, and asked that drug manufacturers add a 'black box' warning to prescribing information for these drugs. Most deaths were due to either cardiac or infectious causes, the two most common immediate causes of death in dementia in general. Clinicians, patients, and caregivers are left with unclear choices of treatment for dementia patients with psychosis and/or severe agitation. Not only are psychosis and agitation common in persons with dementia but they also frequently cause considerable caregiver distress and hasten institutionalization of patients. At the same time, there is a paucity of evidence-based treatment alternatives to antipsychotics for this population. Thus, there is insufficient evidence to suggest that psychotropics other than antipsychotics represent an overall effective and safe, let alone better, treatment choice for psychosis or agitation in dementia; currently no such treatment has been approved by the FDA for these symptoms. Similarly, the data on the efficacy of specific psychosocial treatments in patients with dementia are limited and inconclusive. The goal of this White Paper is to review relevant issues and make clinical and research recommendations regarding the treatment of elderly dementia patients with psychosis and/ or agitation. The role of shared decision making and caution in using pharmacotherapy for these patients is stressed.

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“…Hence the vitiation of Vata in old age leads to manifestation of physical and mental disorders [3][4][5] .…”

Section: Psychological Disorders In Old Agementioning

confidence: 99%

Psychological Problems of the Aged and Its Management

Sahoo¹,

Panigrahi²,

Rao³

et al. 2013

Int. J. Res. Ayurveda Pharm.

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Aging is an inevitable biological phenomenon resulting from intrinsic and extrinsic damage to the various organs and systems. One does not know when old age begins. The "biological age" of a person is not identical to the "chronological age". Victor Hugo once said 40 is the old age of youth where as 50 is the youth of old age. So in countries like India we are considering the age of 60 as the start of old age. The decline in cognitive functions is very common consequence of aging. It is significantly associated with poor self-perception, depression, fear, worry, anxiety, decreased memory, angry etc., which are sometimes life-threatening conditions. In Astanga Ayurveda, Jara Chikitsa exists as a separate branch but detailed descriptions are not available. We got the scattered references regarding prevention of Jara and management of old age problems. Mainly Rasayanas of different types are mentioned for prevention as well as promotion of health in old age. The Rasayana drugs and Panchakarma. Therapies not only promote the physical health but beneficial effects also seen on brain and its functional areas. Different Rasayanas and Panchakarma therapies with their effects will be detailed described in full paper.

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Synopsis of Psychiatry

Cited by 118 publications

References 0 publications

Cannabis and other variables affecting age at onset in a schizophrenia founder population

Cannabis and other variables affecting age at onset in a schizophrenia founder population

ACNP White Paper: Update on Use of Antipsychotic Drugs in Elderly Persons with Dementia

Psychological Problems of the Aged and Its Management

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