No abstract

Background: Kaposi sarcomais a low-grade malignant vascular lesion, which has different histological variants. Pyogenic granuloma-like Kaposi sarcoma is an unusual type of this tumor, which presents as anexophytic small nodule surrounded by an epidermal collaret mimicking pyogenic granuloma yet it has immunohistopathologic features of Kaposi sarcoma. Case Presentation: A 57-year old male with 2 exophytic lesions on the left hand and left foot for 3 months was presented to our center. Both lesions were excised and diagnosis of Kaposi sarcoma was confirmed by histopathology and immunohistochemistry. Human herpesvirus 8 DNA was detected by the polymerase chain reaction in the lesions. Conclusions: Immunostaining methods should be considered in pyogenic granuloma-like lesions with unusual presentation.

No abstract

No abstract

No abstract

Background Cherry angioma is the most common type of acquired cutaneous vascular proliferation which would increase with aging due to some angiogenic factors but the exact pathogenesis is unknown. Usually angiogenic factors are synthesized in human body to compensate occlusive effects of atherogenic agents such as serum lipids. Our hypothesis was that increased levels of these angiogenic factors could be a trigger for development of cherry angioma. This study has been designed to compare frequency of dyslipidemia in subjects with and without cutaneous cherry angioma. Methods In this case-control study, 122 cases with cherry angioma and 122 control subjects without cherry angioma were enrolled. Demographic characteristics, number of the cherry angioma lesions, and serum lipid profile were collected for all subjects. The data was analyzed using SPSS 18 software. Results Mean levels of the total cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein were higher in patients with cherry angioma compared to control subjects in which differences were significant for total cholesterol, low-density lipoprotein, and triglyceride (P < 0.05) but not for high-density lipoprotein level. Conclusion Serum lipids may have a role in producing angiogenic factors and development of cherry angioma and it seems logical to evaluate lipid profile in these cases.

No abstract

No abstract