Vascular endothelial growth factor (VEGF) is expressed in human endometrium, but the cellular source of VEGF for endometrial angiogenesis has not been determined. In the present study the relationship between focal VEGF associated with microvessels and endothelial cell proliferation was examined in three layers of human endometrium at various stages of the menstrual cycle (menstrual, proliferative and secretory). Immunohistochemical analysis of full thickness endometrium from 18 hysterectomy samples without endometrial pathology were examined. The percentage of proliferating vessels was higher in proliferative compared to secretory endometrium, but this was only statistically significant in the basalis layer. A significantly greater percentage of VEGF-expressing microvessels was observed in proliferative than secretory endometrium (P < 0.05). The most VEGF-expressing microvessels were observed in the subepithelial capillary plexus, followed by the functionalis and least were present in the basalis. There was a significant correlation between focal VEGF-expressing microvessels and proliferating vessels for the subepithelial capillary plexus (R(s) = 0.70, P = 0.008), the functionalis (R(s) = 0.70, P = 0.001) and the basalis (R(s) = 0.76, P < 0.001). Focal VEGF associated with microvessels was found in marginating and adherent neutrophils. These data suggest that neutrophils in intimate contact with endometrial endothelium may be a source of intravascular VEGF for vessels undergoing angiogenesis by elongation or intussusception, particularly during the proliferative phase of rapid endometrial growth.
FlyOver Urip Sumoharjo KM.4 Makassar merupakan jalan layang yang dibangun oleh Pemerintah Kota Makassar guna untuk memecah kemacetan yang sering terjadi malah menambah kemacetan di waktu-waktu tertentu karena adanya aktivitas lain yang dilakukan oleh masyarakat dan menjadi masalah spasial pada flyover. Penelitian ini bertujuan mengungkapkan bentuk-bentuk aktivitas yang dilakukan oleh aktor dan kekuatan yang membentuk aktivitas. Lokasi penelitian yaitu di FlyOver Urip Sumoharjo KM.4 Makassar. Metode penelitian dilakukan dengan metode kualitatif. Pengumpulan data dilakukan dengan wawancara, kuesioner, observasi dan studi pustaka. Analisis data dengan menggunakan analisis deskriptif. Hasil dari penelitian mengungkapkan kekuatan yang membentuk aktivitas di FlyOver adalah karena adanya kesatuan aktor-ruang-waktu. Posisi aktor adalah sebagai unsur yang berperan utama dalam memaknai ruang (space) menjadi sebuah tempat (place), juga merupakan unsur yang menentukan dalam pembentukan sebuah peristiwa. Ruang sebagai unsur yang mewadahi berlangsungnya sebuah kegiatan atau peristiwa, sedangkan waktu adalah unsur yang "seolah-olah" mengatur, mengendalikan dan menentukan kapan peristiwa itu terjadi dan kapan peristiwa itu berhenti. Ketiga unsur aktorruang-waktu dalam sebuah peristiwa senantiasa bergerak, berubah, bergeser, berganti dan selalu menjadi satu kesatuan yang utuh. Kata kunci : Ruang Publik; FlyOver ; Makassar Abstract_ Flyover on Urip Sumoharjo KM.4 in Makassar is an overpass that built by the Makassar city government in order to solve the traffic jam that often occur becoming the increasing of traffic jam at a particular time because of the other activities that held by people of the city and which is the spatial problems of flyover. The study aimed to reveal the forms of activities that held by its actors, and the strenght that formed the activities. The location of the Research is the flyover on Urip Sumoharjo KM.4 in Makassar. The method of research conducted with qualitative methods. Data collection is taken by interviews, questionnaires, observations and literature study. Data analysis used descriptive analysis. The results of the study revealed the strength that formed the activity on The flyover because of the unity of its actor, space and time. The position of the Actor is an element that played a main role in defining the space into a place, is also a decisive element in forming an event. Space is an element that accommodates an activitry or an event happened, while time is an element that seemed to regulate, control and determine when the eventshappened and when it stopped. The third element of the actor, space and time in an event constantly moved, changed, shifted and always be one whole unity.
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