Melanoma composed of melanocytes may arise in the skin or other tissues harboring melanocytes, such muco-cutaneous junctions, mucosa including the conjunctiva, iris, choroids and substantia nigra.1 Metastases to the skin and subcutaneous tissues from a malignant melanoma are less common. A case of multiple painless nodules on the body that revealed metastatic deposits of melanoma on histopathological examination is being reported.
Diabetes mellitus is a metabolic derangement associated with abnormalities in major metabolic pathways like carbohydrate, amino acid and lipid. It is featured by hyperglycemia, insulin deficiency, with long-term complications affecting different organs like brain, eyes, heart, kidney and limbs 1 .This disorder is divided into insulin dependent diabetes mellitus (IDDM)-Type 1 Diabetes and non-insulin-dependent diabetes mellitus (NIDDM)-Type 2 Diabetes. IDDM is an auto immune condition raised due to damage of insulin producing pancreatic beta cells. NIDDM is
Four cases of Mycetoma especially among farmers were confirmed both by demonstrating granules in histopathological sections and by isolating Madurellagrisea in two patients, Madurellamycetomatis in one and Nocardia asteroids in one, following retrieval trauma. Eumycotic and Actinomycotic agents produce severe morbidity. One cases of Actinomycoticmycetoma responded to Trimethoprim-Sulphamethasone and the remaining three had antifungal Ketaconazole therapy for six months and did not return up for further follow up. These four cases are being reported here for its unusual clinical manifestations of multiple blisters in the extremities without the sinus tract formation and clinically mycetoma could not be diagnosed and indicates the need for biopsy examination and mycology culture.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.