Effect of Artemisia Absinthium on the Neurochemical Profile of Streptozotocin Induced Diabetic Rat Brain

Abstract

Diabetes mellitus is a metabolic derangement associated with abnormalities in major metabolic pathways like carbohydrate, amino acid and lipid. It is featured by hyperglycemia, insulin deficiency, with long-term complications affecting different organs like brain, eyes, heart, kidney and limbs 1 .This disorder is divided into insulin dependent diabetes mellitus (IDDM)-Type 1 Diabetes and non-insulin-dependent diabetes mellitus (NIDDM)-Type 2 Diabetes. IDDM is an auto immune condition raised due to damage of insulin producing pancreatic beta cells. NIDDM is