Summary
An unusual Rh gene complex was found in six apparently unrelated Swedish families; for it the symbols D(C)(e) are used: the brackets represent weakness of the corresponding antigens. The gene complex is similar to the so far described only in a single Negro family.
Résumé
Un complexe de gènes Rhésus inhabituel a été trouvé dans six families suédoises, à première vue non apparentées; pour ce complexe, les symboles D(C)(e) ont été utilisés: les parenthèses indiquent la faiblesse de l'antigène correspondent. Ce complexe de gènes est identique au complexe décrit dans une seule famille de race noire.
Zusammenfassung
Bei sechs offenbar unter sich nicht verwandten schwedischen Familien wurde ein ungewöhnlicher Rh‐Genkomplex gefunden. Er wird mit dem Symbol D(C)(e) bezeichnet, wobei die Klammern auf die Schwäche der betreffenden Antigene binweisen. Dieser Genkomplex gleicht dem , welcher bisher erst bei einer einzelnen Negerfamilie beschrieben wurde.
Summary.
The conception that Rh incompatibility between mother and foetus is the cause of familial erythroblastosis foetalis (morbus haemolyticus neonatorum) to far more than 90% has considerably helped on the diagnosis and prognosis of this complaint. On the other hand, the elucidation of the pathogenesis has meant no material advance in the therapy, apart from the use of Rh‐negative blood in transfusions to children with this disease. Judging from his own material, the author considers this improvement of the transfusion therapy to imply only a very modest step forward in the results of our treatment
Guiding‐lines are given for practical experiments to find a protective substance against the haemolytic action of the Rh antibodies in the child's body. It is preliminarily stated that a certain effect of this kind might possibly be ascribed to progesterone. The risk of contracting morbus haemolyticus neonatorum is not decreased for children taken from Rh‐immunised women by means of a caesarean section before the onset of labour, not even if this is done several weeks before term.
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