It is known that the seeds of avocado (Persea americana Mill.) are one part of the avocado widely used to treat various diseases, including diabetes. Based on the previous research, avocado seeds contain flavonoids with the potency as inhibitors of the enzyme α-glucosidase. The research aimed to determine the potency of ethanol extracted by meceration using 96% ethanol. The inhibitory activity was assayed using ELISA (Enzyme-Linked Immunosorbant Assay) reader measured at the wavelength of 405 with an acarbose comparator. The results showed that the ethanol extract of avocado seeds had an inhibitory activity included in the active category based on IC50 value of 34.300 µg/mL. Meanwhile, the acarbose had inhibition activity included in the very active category with an IC50 value of 0.253 µg/mL.
Chronic exposure to ultraviolet light from the sun will cause changes in skin structure and oxidative stress on the skin. The effects can be in the form of acute changes such as erythema, pigmentation and photosensitivity, as well as long-term effects of premature aging and skin damage. Sun Protection Factor (SPF) is a universal indicator that explains the effectiveness of a product or substance that is UV protection. Natural ingredients that can be used as UV protection are button mushrooms (Agaricus bisporus). This study aims to determine UV light protection activity in the ethanol extract of button mushrooms (Agaricus bisporus) based on the SPF values analyzed by UV-Vis spectrophotometry at wavelengths of 290-320 nm. The results showed that at concentrations of 1% and 2% had a medium SPF category with SPF values of 17,762 and 28,643. For concentrations of 3% and 4% it has a high SPF category with SPF values of 30,592 and 31,325. The higher the concentration used, the better the SPF value.
Pomelo citrus (Citrus maxima (Burm) Merr) is a fruit plant that has the potential to be developed for health. Pomelo fruit contains lycopene, flavonoids and vitamin C which can provide antioxidant activity. The purpose of this study was to determine the potential antioxidant activity of ethanol extract and fraction of n-hexane of pomelo citrus using quercetin as a comparison. Extraction of pomelo citrus fruit using the maceration method with liquid-liquid fractionation using water and n-hexane (1: 3 v / v). Testing of antioxidant activity using the DPPH (1,1-Diphenyl-2-picrylhidrazil) method is based on the ability of the sample to capture DPPH free radicals which are characterized by purple to yellow discoloration and a decrease in the absorbance value of DPPH which has reacted with samples in certain concentrations. Absorbance measurements using a UV-Vis spectrophotometer at a wavelength of 514,942 nm. The results showed that the IC50 value of quercetin was 6.55 µg / mL which was a strong antioxidant, while the IC50 value of the ethanol extract of pomelo citrus fruit was 2882.26 µg / mL and IC50 value of the n-hexane fraction of pomelo orange was 3668,44 µg / mL which is a weak antioxidant category. Kata kunci : Antioxidants, Ethanol Extract, n-Hexane Fraction, Pomelo citrus (Citrus maxima (Burm) Merr
Chronic exposure to ultraviolet light from the sun will cause changes in skin structure and oxidative stress on the skin. The effects can be in the form of acute changes such as erythema, pigmentation and photosensitivity, as well as long-term effects of premature aging and skin damage. Sun Protection Factor (SPF) is a universal indicator that explains the effectiveness of a product or substance that is UV protection. Natural ingredients that can be used as UV protection are button mushrooms (Agaricus bisporus). This study aims to determine UV light protection activity in the ethanol extract of button mushrooms (Agaricus bisporus) based on the SPF values analyzed by UV-Vis spectrophotometry at wavelengths of 290-320 nm. The results showed that at concentrations of 1% and 2% had a medium SPF category with SPF values of 17,762 and 28,643. For concentrations of 3% and 4% it has a high SPF category with SPF values of 30,592 and 31,325. The higher the concentration used, the better the SPF value.
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