Aim: To examine the clinical characteristics of patients with acute appendicitis Study design: A cross-sectional study Place and Duration: This study was conducted at Liaquat University Hospital Jamshoro / Hyderabad from March 2021 to March 2022. Methodology: Presentstudy included 118 patients who went through emergency appendectomy for acute appendicitis. The study evaluated the patient's clinical profile who presented with acute appendicitis. A detailed history was taken, a clinical examination was performed, and tests such as a complete blood test and ultrasonography were performed. Patients of either gender, above 10 years of age, and with clinical diagnoses of acute appendicitis were incorporated in the study. Patients having an appendicular mass or right ureteric/renal colic were excluded from the study. Results: In the current study themean age of patients was 27.56 ± 9.8 years. Out of 118 patients, 71 (60.1%) were males, and 47 (39.83%) were females. We observed thepredominance of malesin the current study. Majority of the patients presented with complaints of right iliac fossa pain (98.3%) and migration of pain (67.8%). Nausea and anorexia were present in 86.4% of cases, and vomiting was present in 84.7% of cases.Tenderness was observed in right iliac fossa in all patients while Dunphy sign (59.3%), guarding (63.5%), rebound tenderness (69.4%), rigidity (5.9%), Psoas sign (45.7%), Rovsing sign (35.5%)and Obturator sign (21.1%). Conclusion: Males are more likely to have acute appendicitis than females between 10 and 30 years of age. The most common signs and symptoms were discomforts, anorexia, nausea/vomiting, and abdominal pain. Tenderness, guarding, and rebound tenderness were the most prevalent symptoms.
Aim: The current study was designed to assess the simultaneous presence of H. pylori in gastric and gallbladder mucosa in the patients of acute cholecystitis or symptomatic cholelithiasis. Study design: Cross sectional study Place and duration: This study was conducted at Liaquat University Hospital Hyderabad, Pakistan from March 2020 to March 2021. Methodology: A total of 43 patients suffering from acute cholecystitis and symptomatic cholelithiasis were selected. Their age, gender, and the presence of H. pylori in the gallbladder and gastric mucosa was determined and recorded. The results were statistically analyzed by SPSS version 22. Results: Out of the 43 patients, 20 were male, and 23 were female. Recorded mean age was 54.8±9.9 years and 22 (51.2%) had acute cholecystitis and the remaining 21 (48.8%) had cholelithiasis. In the gastric mucosa, in 14 patients (32.6%) H. pylori was positive. Similarly, in the gall bladder; it was positive in 19 patients (44.2%). In 6 patients (13.9%) i.e. in 4 men and 2 women, H pylori was simultaneously present in both gallbladder and gastric mucosa. No particular relationship was observed in the H. pylori’s presence or absence in gallbladder and gastric mucosa. Conclusion: The presence of H. pylori in gallbladder plays a critical role in the gallbladder’s infection. However, its simultaneous presence in gastric mucosa is not a good standard to assess biliary diseases. Keywords: H. pylori, Cholecystitis, Cholelithiasis, Gallbladder, Gastric mucosa
Aim: To evaluate the quality of bowel preparations concerning the Boston Bowel Preparation Score (BBPS) and to analyze the administration, ease, palatability, and side effects of practices. Study design: Cross-sectional study Place and Duration: this study was conducted in Liaquat University of Medical and Health Sciences Jamshoro from October 2021 to March 2022 Methodology: The present study incorporated 132 patients who visited the hospital for a colonoscopy. Patients above 18 years of age were included, whereas patients with surgical procedures were excluded from the study. Participants were evaluated through pre-designed proforma for demography, dietary recommendations, side effects, procedure indications, bowel preparations, and patient ease of the bowel preparations. BBPS was used to access the bowel preparation. A score ≥ 5 was regarded as satisfactory. Results: Out of 132 patients, 73 (55.3%) were males. Seventy-one (53.8%) patients received Polyethylene glycol-based bowl preparation, and sixty-one (46.2%) patients received sodium phosphate-based preparation. Chronic constipation was the most typical cause of colonoscopy. Common side effects were vomiting (12.1%), nausea (1.5%), and bloating (3%). More than half of them responded that the preparations were palatable. A satisfaction rate of 80.3% was observed in patients with both preparations. BBPS of above five was observed in 109 (82.6%) patients. Conclusion: Polyethylene glycol and sodium phosphate preparations have been widely used in clinical practices for cleansing the colon. Sodium phosphate-based preparation was found more effective. Keywords: Bowel cleansing agents, Colonoscopy, Endoscopy, Polyethylene Glycol, Sodium phosphate.
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