Flooding in urban and rural areas is one of the utmost challenges to human safety. Destruction of the properties is the main issue in urban areas and damage to the agriculture practices in the rural area. Flood risk is rising significantly all over the globe. The regional water cycle and water resource availability are governed by the rainfall event, which is a fundamental meteorological parameter. The objective of the study is to examine the rainfall variability for 25 years from the period from 1995 to 2020 for monthly and annual rainfalls in the part of Nanjangud taluk, Mysore district, Karnataka. During the last three years that is 2017 to 2019 during the southwest monsoon, it is noted that the severity of flood increased in the surrounding of Nanjangud town, due to the heavy rainfall and excess amount of water released has augmented the inflow source of flooding. The assimilation of Remotely Sensing (RS) and Geographical Information System (GIS) is capable to generate a sequence of thematic maps that were helpful to create geospatial data for demarcating flood hazard areas. This study discusses the probable flood risk-prone regions of the Kabini river basin near Nanjangud town based on the multi-ring buffered layer analysis. The buffered layers created for the radius of 250m, 500m 750m, and 1000m were overlaid on the Sentinel-2 satellite image and topographic map to delineate the flood-affected region. To calculate the slope and drainage density, the SRTM DEM data was used. Structural and nonstructural practices are proposed in this study can be implemented to reduce the probability of the effect of floods.
Background:
Despite the low level of clinical evidence in hydroxychloroquine (HCQ) favor, it was prescribed for pre- and post-exposure prophylaxis in India and worldwide. In absence of a large randomized control trial, the evidence needs to be generated through observation study, hence the study was conducted to find the evidence for prophylaxis of HCQ.
Materials and Methods:
A multi-centric cross-sectional study involving government hospitals was chosen for serosurvey conducted from August 21, 2020, to November 20, 2020. Questionnaire was adopted from WHO. Data about chloroquine (CQ) use among health-care workers (HCWs) were added and the duration of CQ intake was also noted.
Results:
A total of 2,224 HCWs were recruited. The mean duration of time of taking HCQ was 7.1 weeks (standard deviation ± 6.1 weeks, median = 4 weeks with IQR, 3–10 weeks). Training on personal protective equipment (PPE), knowledge of handwashing, direct care to the patient, availability of alcohol hand rub, close contact with the patient, duration of contact, and usage of PPE were associated with HCQ intake. The antibody formation in group taking HCQ was 16.9% compared to 19.8% not taking it (
P
= 0.08). The Chi-square for linear trend for weeks of HCQ intake and antibody formation. However, the same was not statistically significant (Chi-square = 3.61,
P
= 0.06).
Conclusion:
Our study did not find a statistically significant association in the large multicentric study. The absolute difference of 2.9% in the two groups may not be sufficient to warrant its widespread use for prophylaxis.
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