In this article we report a case of rare composite odontogenic tumor, having features similar to adenoid ameloblastoma with dentinoid described previously. The histological features are similar to both ameloblastoma and AOT and show evidence of induction in the form of dentinoid. The patient was a 35 years old female. The lesion was located on right side of the mandible in premolar‐molar area. Radiograph revealed unilocular radiolucency with foci of radio‐opacities. On gross examination the tumor was cystic at places. The histopathological features consists of two patterns, one resembling AOT and other plexiform ameloblastoma. The formation of dentinoid like material was observed in association with odontogenic epithelium. Apart from this the presence of ghost cells was a unique histopathological feature.
This article also reviews the various cases reported in literature and provides an insight into the nature of composite odontogenic tumor. To date only 12 cases of this uncommon composite odontogenic tumor are reported in the literature.
The calcifying ghost cell odontogenic cyst (CGCOC) was first described by Gorlin et al. in 1962. Calcifying ghost cell odontogenic cyst is comparatively rare in occurrence, constituting about 0.37% to 2.1% of all odontogenic tumors. The most notable features of this pathologic entity are histopathological features which include a cystic lining demonstrating characteristic “Ghost” epithelial cells with a propensity to calcify. In addition, the CGCOC may be associated with other recognized odontogenic tumors, most commonly odontomas. There are variants of CGCOC according to clinical, histopathological, and radiological characteristics. Therefore a proper categorization of the cases is needed for better understanding of the pathogenesis of each variant. Here, we report a classical case of calcifying odontogenic cyst along with a brief review of literature.
The intraosseous osteolytic lesions mainly involving the metaphyseal region of vertebrae and long bones were diagnosed as aneurysmal bone cysts (ABCs). Further, an ABC was known as an ossifying hematoma. It is considered an expanding osteolytic lesion consisting of blood-filled spaces of variable sizes separated by connective tissue septa containing trabeculae of osteoid tissue and osteoclast giant cells. It is frequently reported to involve long bones; however, only 1.9% prevalence is seen in jaw bones. It represents a very small percentage of all non-odontogenic tumors. ABC shows variations in age prevalence and its clinical presentation may be challenging to the surgeon. In addition, ABC may occur in association with other primary bone pathologies like ossifying fibroma, fibrous dysplasia, and giant cell tumor; such entities are known as ABC plus lesions. Here we present a classic case of ABC plus lesion.
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