Now-a-days intraoperative consultation plays an important role in proper management of patients. Intraoperative crush cytology is widely used in the rapid diagnosis of various tumors, but a very few reports describe the utility of intraoperative cytology for bone lesions. 7 Here, we report a case of vertebral chondroblastoma diagnosed on intraoperative crush smear cytology and later confirmed on histopathology. This case highlights the role of crush cytology in the rapid intraoperative diagnosis of bone tumors.In this brief report, we describe the cytological features of chondroblastoma and discuss its differential diagnosis. | C ASE H I STOR YA 17-year-old male presented with one-year history of back pain.He also complained of progressive weakness and numbness of both lower limbs for 1 month prior to the consultation. His routine investigations were within normal limits. Magnetic resonance imaging (MRI) spine revealed a well defined extradural mass measuring approx 6 cm 3 5 cm 3 3 cm involving predominantly right posterior segment of D 6-7 vertebrae with expansile soft tissue component (Figure 1). The mass showed an extradural intraspinal extension causing cord compression and edema. With a tentative radiological diagnosis of lymphoma, D 6-7 laminectomy was done and near total excision of the tumor was carried out. Postoperatively, the patient recovered well and was able to walk without difficulty. | Intraoperative crush cytologyThe tissue was relatively firm to make the smears. The smears showed dense tissue fragments with well spread cellular smears surrounding
The fungi in the order of Mucorales commonly target diabetics and other immunocompromised hosts, producing fatal respiratory and or CNS infections. Gastrointestinal mucormycosis is uncommon and seldom diagnosed in living patients due to nonspecific clinical manifestations. We report a case of gastric mucormycosis in an immmunocompetent male patient, diagnosed by imprint cytology-a rare site and a rare setting. To the best of our knowledge, this is only the second report of gastric mucormycosis being diagnosed on cytology. As the disease is rapidly progressive and often fatal, early diagnosis is critical to the patient survival. Imprint cytology or brush cytology is extremely useful for the rapid diagnosis of gastric mucormycosis as these organisms are morphologically distinct. Familiarity with the cytomorphology of these organisms assists in the correct diagnosis of this disease. Diagn. Cytopathol. 2016;44:820-822. © 2016 Wiley Periodicals, Inc.
A 52-year-old non smoker female patient presented with the complaints of pain in abdomen associated with heartburn and nausea. She was operated case of hysterectomy for squamous cell carcinoma of uterine cervix. She was given radiotherapy for the same two years back but the time period and dosage of radiation was not available due to loss of records. On examination, she was complaining of loss of weight approximately 10 to 15% of body weight and anorexia since six months. CT abdomen showed heterogeneously enhancing mass in upper retroperitoneum directly involving third part of the duodenum [Table/ Fig-1]. Radiological provisional diagnosis was lymph node mass with secondary involvement of duodenum. Upper gastrointestinal endoscopic examination showed multiple nodular areas at periampullary region extending beyond ampulla. Endoscopic biopsy from periampullary region was taken. Multiple tiny grey brown tissue bits were submitted for histopathology examination. Sections were prepared by paraffin embedding method and stained with haematoxylin and eosin. Microscopic examination revealed normal duodenal mucosa with sparse inflammatory infiltrate [Table/ Fig-2]. The duodenal wall was infiltrated by squamous islands. It showed malignant squamous cells with pleomorphism and hyperchromasia [Table/ Fig-3]. So, the final diagnosis was metastasis of squamous cell carcinoma involving duodenum was done. Further management of patient was not known due to loss of follow up. DisCussionCarcinoma cervix is the most common malignancy in Indian women, with an incidence of 19 to 44 per 100 000 women [1]. It is well known that carcinoma of cervix exhibits a low incidence of distant metastases and more often spreads locally. It is exceedingly rare for squamous cell carcinoma (SCC) of the cervix to clinically present with symptoms related to small bowel metastases. The lymphatic system is the usual route through which cervical cancer spreads to distant regions and there is rarity of the blood vessel invasion. Metastasis to the lymph nodes at the bifurcation of the aorta is invariably accompanied by distant spread [2]. Most of the reported cases of squamous cell carcinoma in the pyloroduodenal region are from lung primary [1].Although metastatic lesions in the GIT are rare, they do occur. They usually present as single and primary carcinoma-like lesions, with the stomach and duodenum most commonly involved [3]. Metastatic aBstRaCtWe report a case of squamous cell carcinoma of uterine cervix metastasizing to the duodenum through lymphatics. Para-aortic group of lymph nodes were involved which ultimately infiltrated the duodenum. On endoscopic examination, peri-ampullary growth was noted. Endoscopic biopsy from the growth was studied by routine histopathology and metastasis of squamous cell carcinoma involving duodenum was reported.
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