Now-a-days intraoperative consultation plays an important role in proper management of patients. Intraoperative crush cytology is widely used in the rapid diagnosis of various tumors, but a very few reports describe the utility of intraoperative cytology for bone lesions. 7 Here, we report a case of vertebral chondroblastoma diagnosed on intraoperative crush smear cytology and later confirmed on histopathology. This case highlights the role of crush cytology in the rapid intraoperative diagnosis of bone tumors.In this brief report, we describe the cytological features of chondroblastoma and discuss its differential diagnosis. | C ASE H I STOR YA 17-year-old male presented with one-year history of back pain.He also complained of progressive weakness and numbness of both lower limbs for 1 month prior to the consultation. His routine investigations were within normal limits. Magnetic resonance imaging (MRI) spine revealed a well defined extradural mass measuring approx 6 cm 3 5 cm 3 3 cm involving predominantly right posterior segment of D 6-7 vertebrae with expansile soft tissue component (Figure 1). The mass showed an extradural intraspinal extension causing cord compression and edema. With a tentative radiological diagnosis of lymphoma, D 6-7 laminectomy was done and near total excision of the tumor was carried out. Postoperatively, the patient recovered well and was able to walk without difficulty. | Intraoperative crush cytologyThe tissue was relatively firm to make the smears. The smears showed dense tissue fragments with well spread cellular smears surrounding

The fungi in the order of Mucorales commonly target diabetics and other immunocompromised hosts, producing fatal respiratory and or CNS infections. Gastrointestinal mucormycosis is uncommon and seldom diagnosed in living patients due to nonspecific clinical manifestations. We report a case of gastric mucormycosis in an immmunocompetent male patient, diagnosed by imprint cytology-a rare site and a rare setting. To the best of our knowledge, this is only the second report of gastric mucormycosis being diagnosed on cytology. As the disease is rapidly progressive and often fatal, early diagnosis is critical to the patient survival. Imprint cytology or brush cytology is extremely useful for the rapid diagnosis of gastric mucormycosis as these organisms are morphologically distinct. Familiarity with the cytomorphology of these organisms assists in the correct diagnosis of this disease. Diagn. Cytopathol. 2016;44:820-822. © 2016 Wiley Periodicals, Inc.

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Papillary meningioma is a rare, aggressive variant of meningioma. It accounts for less than 1% of all meningiomas. It is categorized as WHO grade III due to high rate of recurrence and metastasis. Histopathologic features of papillary meningioma are well described, but cytomorphology is rarely been described. We report a case of papillary meningioma, diagnosed on intraoperative crush cytology and later confirmed on histopathology. Papillary meningioma possesses characteristic cytological features. Along with the cellular meningothelial features, radial arrangement of cells around thin and thick walled hyalinised blood vessels gives the diagnostic clue. In addition, knowledge of clinical and radiological features is extremely helpful to arrive at the correct diagnosis and to differentiate it from other papillary lesions involving central nervous system. Due to aggressive clinical course and poor prognosis of papillary meningioma, a timely recognition of the diagnosis is desirable and helpful for rationalizing approaches to therapy.

An “Intra-cranial space occupying lesion” (ICSOL) is defined as a mass in the cranial cavity with a diverse etiology like benign or malignant neoplasm, inflammatory or parasitic lesion, haematoma or arterio-venous malformation. The aim was to study the histomorphological spectrum of intracranial space occupying lesions at a tertiary care centre hospital in order to give accurate pretherapeutic diagnosis to facilitate better therapeutic results. This prospective and descriptive type of study of two years duration was carried out from November 2017 to October 2019 in Govt. Medical College and Superspeciality Hospital, Nagpur in the Department of Pathology. A total of 300 samples were received from Department of Neurosurgery. Detailed collection of clinical data was done in all patients regarding age, sex, clinical symptoms and radiological findings.The samples were received in 10% formalin and subjected to routine histopathological processing. Slides prepared were stained with hematoxylin and eosin stain. Special stains were done wherever required. Total 300 cases were studied of which 261 cases (87%) were neoplastic in nature and 39 cases (13%) were non neoplastic. Amongst primary tumours, most common were gliomas (48%) followed by meningiomas (20%) and schwannomas (9%). ICSOLs can present with nonspecific clinical features. Radio diagnostic investigations are helpful adjunct tools but cannot give exact diagnosis. Histopathological examination remains a gold standard for diagnosing and grading of tumours on which basis clinician can decide further line of management.

Mature cystic teratomas (MCTs) (dermoid cyst) make up almost 20% of all ovarian neoplasms and 88% are unilateral. They constitute the most common ovarian tumor in childhood. However, it is sparsely seen in postmenopausal woman. Malignant transformation is seen in approximately 2% of all cases of MCT and risk gets doubled in postmenopausal woman. Here, we present a case report of MCT occurring in postmenopausal multiparous woman masquerading as lithopaedion on imaging which is a rare phenomenon. Thus, the mystery behind Monsters egg is finally resolved by morphology.

Amyloidosis is a wide spectrum of disease characterized by extracellular deposition of misfolded protein which has common morphological, structural, and staining properties but differs in their protein composition. Hepatic amyloidosis can present as clinicoradiological dido and requires liver biopsy and ancillary histopathological techniques not only to attest the diagnosis but also for typing of amyloidosis. Here, we report a case of hepatic amyloidosis with preserved liver function test despite having massive hepatomegaly.

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