Os relatos de portadores de insuficiência renal crônica em hemodiálise sobre as alterações em seu cotidiano após o início do tratamento motivaram indagar quais aspectos têm alterado a qualidade de suas vidas (QV). Estudo descritivo exploratório objetivando avaliar a QV dos portadores de doença renal crônica em hemodiálise, por meio do instrumento Kidney Disease and Quality of Life Short Form (KDQOL-SF). Foram entrevistados 72 pacientes em Goiânia - Brasil, entre abril e maio de 2005. A maioria (52,8%) era do sexo masculino, idade média 51,1 ± 16,6 anos, católica, renda menor que 2 salários mínimos ou não trabalhava, tinha companheiro fixo e fazia hemodiálise há menos que 60 meses. Os maiores escores foram obtidos nas Dimensões “Estímulo por Parte da Equipe de Diálise” (88,37), “Qualidade da Interação Social” (80,83) e “Função Cognitiva” (80,74). As Dimensões “Função Física” (20,49) e “Papel Profissional” (22,22) obtiveram os menores escores. A percepção dos indivíduos nas Dimensões do KDQOL-SF foi influenciada pela religião, gênero, idade, tempo de tratamento, presença de companheiro fixo, escolaridade, se residia sozinho e pelo trabalho. Conclui-se que o indivíduo em hemodiálise sofre alterações na sua QV, as quais indicam que aspectos estão influenciando-a negativamente e que podem direcionar ações dos profissionais.

(117,0 ± 13,9), cuidado compassivo (69,1 ± 8,6), colocar-se no lugar do paciente (8,5 ± 3,0) e tomada de perspectiva (39,4 ± 6,3 69.4 (± 8.0) and 68.8 (± 9.4), for the capacity to place themselves in the patient 's position, 8.4 (± 3.0) and 8.6 (± 2.9), and looking at things in perspective, 39.1 (± 6.3) and 39.7 (± 6.3)

Objective: to analyze the functional health literacy (FHL), i.e., understanding and knowledge about chronic renal disease of 60 patients in pre-dialytic treatment. Method: this is a cross-sectional study. FHL was measured by B-TOFHLA; and the knowledge, by questionnaire. Pearson correlation and Chi-square tests were carried out as well as linear regression models. Results: all respondents presented inadequate FHL, and most showed insuffi cient knowledge about the disease and treatment. Low schooling was a predictive factor for worst FHL scores. Insuffi cient knowledge was related to age and compromised cognition. Conclusion: although association between predictive variables has not been found, limited capability to obtain and use health-related information and insuffi cient knowledge about their own condition and treatment can contribute to worse outcomes for CKD. Appropriate intervention strategies are necessary to deal with limited FHL and also greater knowledge and ability of professionals to deal with the matter.

The results obtained in the present study, with respect to the presence of the high-risk HPV16 and HPV18 genotypes, highlight the importance of human papilomavirus vaccination in the control of oral cavity and oropharynx carcinomas.

This study was conducted in order to investigate the implications of the R72P polymorphism in the TP53 gene in breast cancer risk. The enlightenment of this matter might provide a piece of information about the potential implications of this polymorphism in patient risk. A meta-analysis was conducted considering a large sample size from studies with conflicting results on the R72P polymorphism in breast cancer patients. Relevant studies were selected from PubMed and SciELO databases for data extraction and statistical analysis. Database was built according to the continent and considering the genotype frequencies, sample size and genotyping methodology. The dominant models (RR vs RP + PP and RR + RP vs. PP), homozygous (RR vs. PP), heterozygous (RR vs. RP and RP vs. PP) and the allele (R vs. P) were used. Genotype frequencies were summarized and evaluated by χ2 test of heterogeneity in 2×2 contingency tables with 95% CIs. Odds Ratios (OR) were calculated with a fixed-effect model (Mantel-Haenszel) or a random-effect model (DerSimonian-Laird) if the studies were considered homogeneous (P > 0.05) or heterogeneous (P < 0.05), respectively, using BioEstat® 5.0 software. Supported by a large sample size composed by 25,629 cases and 26,633 controls from 41 studies, we found significant association between the R72P polymorphism in the TP53 gene and the breast cancer risk. The overall data shows an increased risk due to the P allele dominant model, but not in Asia where the risk was associated with the R allele and R dominant model.