Robust evidence on the pathogenesis and pathological findings of most diseases is based on autopsy examination. In view of the many knowledge gaps still hindering our current understanding of SARS-CoV-2 infection, post-mortem studies in this life-threatening disease are urgently needed. However, due to logistic and especially biohazard challenges less than 50 post-mortem examinations have been conducted in patients dying from COVID-19; most of them adult males with comorbidities. A few years ago, our group developed and validated in all age-groups a standardised minimally invasive autopsy (MIA) protocol, which might be a safer and more feasible approach to investigate SARS-CoV-2-related deaths. This MIA method is highly accurate in exploring infection-related deaths and may represent a valid post-mortem approach in all settings during the COVID-19 pandemic, especially in those lacking adequate facilities to perform high-risk autopsies. Expansion in the use of MIA might contribute to eliminate the current knowledge gaps on the COVID-19 disease, especially in pediatric deaths and in cases with unusual clinical features.
El presente estudio ofrece un acercamiento al entorno de cultura escrita en el que se desenvolvió la enfermera británica Florence Nightingale durante toda su vida, que mostró una pasión creciente por la escritura. Se comunicó a través de cartas con personas de las más altas esferas de la sociedad victoriana (políticos, intelectuales y científicos), además de mantener una estrecha relación con su familia. Compuso y publicó numerosas obras para el ámbito sanitario y utilizó sistemáticamente el poder omnímodo de la prensa para difundir su obra. Contó con la ayuda inestimable de amigos poderosos e influyentes y en la actualidad su legado escrito se encuentra muy disperso por instituciones de distintos países, siendo en la actualidad una parte de él digitalizado y El legado escrito de Florence Nightingale. Un rico patrimonio de la profesión enfermera
The Written Legacy of Florence Nightingale. A rich heritage of the nursing profession O
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