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The prevalence of obesity is increasing in the industrialized world, so that the World Health Organization considers obesity as a “pandemia” in rich populations. The autonomic nervous system plays a crucial role in the control of energy balance and body weight. This review summarizes our own data and perspectives, emphasizing the influence exerted by autonomic nervous system on energy expenditure and food intake, which are able to determine the body weight. Activation of the sympathetic discharge causes an increase in energy expenditure and a decrease in food intake, while reduction of food intake and body weight loss determines a reduction of the sympathetic activity. On the other hand, pathophysiological mechanisms of the obesity involve alterations of the sympathetic nervous system in accordance with the “Mona Lisa Hypothesis,” an acronym for “most obesities known are low in sympathetic activity.” Furthermore, the parasympathetic influences on the energy expenditure are analyzed in this review, showing that an increase in parasympathetic activity can induce a paradoxical enhancement of energy consumption.

Although most of the clinical studies suggest a worsening of insulin resistance and secretion, the cardiovascular benefits of statin therapy outweigh the risk of developing insulin resistance, thus the data suggest the need to treat dyslipidemia and to make patients aware of the possible risk of developing type 2 diabetes or, if they already are diabetic, of worsening their metabolic control.

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A fourth species of rock crawler (Notoptera: Mantophasmatodea: Mantophasmatidae) is described and figured from an individual preserved in middle Eocene (Lutetian) Baltic amber. Adicophasma grylloblattoides Arillo and Engel, new species, is distinguished from its close relative, A. spinosum Engel and Grimaldi (reinstated), by the reduced pedicel, absence of spines on the maxillae, absence of mesofemoral spination, and proportions of the thoracic segments. The fossil shares with A. spinosum the presence of profemoral spination (confirmed by a new photograph of the holotype) and absence of the dorsal profemoral carina, characters that differentiate Adicophasma from the monotypic Raptophasma; it shares with all Baltic amber Notoptera the absence of the setal fan on the arolium. As noted by previous authors, the former order Mantophasmatodea is related to modern Grylloblattodea, whereas Mesozoic and Paleozoic grylloblattodeans represent a stem group to both. As such, Grylloblattodea and Mantophasmatodea are considered suborders of a single order, Notoptera Crampton (sensu novum), following the recommendation of Engel and Grimaldi (2004). The names for three rock crawlers are emended in order that the specific epithet may match the gender of the generic name: A. spinosum, Mantophasma zephyrum Zompro et al., and Tanzaniophasma subsolanum (Zompro et al.) (nomina emendata). Raptophasmatinae and Ensiferophasmatidae are new synonyms of Mantophasmatidae, while Tanzaniophasmatidae and Austrophasmatidae are newly demoted in rank to a subfamily and tribe of Mantophasmatidae, respectively. A hierarchical classification of Polyneoptera is appended.

In this paper a new species of fossil ground-beetle, Calathus elpis n. sp. (Coleoptera, Carabidae) preserved in a piece of Baltic amber (Eocene) is described. A comparison with extant fauna is made, and paleobiology of the species is studied.

In this paper Litoleptis fossilis sp. nov. a new fossil species belonging to the family Spaniidae (Diptera) is described. This is the first time the genus Litoleptis has been described from the fossil record. A comparison with extant species of Litoleptis and other fossil rhagionoids is done. The fossil is also compared to not closely related Diptera but having convergent wing venation. Palaeoecological and palaeobiogeographical comments are provided.

A new family of eremoneuran Brachycera, the Chimeromyiidae, is proposed for two genera and eight species of a distinctive, monophyletic group of flies in 125–100 myo amber. The new family is related to the Empidoidea and basal Cyclorrhapha. Four new species of Chimeromyia are described: C. pilitibia Grimaldi and Cumming (in Lebanese amber), C. mediobscura Grimaldi and Cumming, C. alava Arillo and Grimaldi (in Spanish amber), and C. burmitica Grimaldi and Cumming (in Burmese amber). A new genus, Chimeromyina Arillo and Grimaldi is also described, for a primitive new species C. concilia (in Spanish amber). New details of these flies are described, particularly of male and female terminalia, and the relationships between this and other eremoneuran families are discussed.