Autonomic Nervous System in the Control of Energy Balance and Body Weight: Personal Contributions

Messina, Antonietta; Luca, Vincenzo De; Viggiano, Alessandro; Arillo, Antonio; Iannaccone, Teresa; Chieffi, Sergio; Monda, Marcellino

doi:10.1155/2013/639280

Cited by 92 publications

(61 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Indeed, orexin A is involved in the activation of thermogenesis related to eating behaviour. The thermogenesis due to food intake is an important factor in the regulation of body weight and the lack of this thermogenesis causes the obesity [31,32]. Moreover, the therapy of rare but dangerous hypothermia caused by clozapine should exclude drugs, which affect the orexinergic system to induce an elevation of body temperature.…”

Section: Discussionmentioning

confidence: 99%

Neuroleptic Drugs Affect Sympathetic and Thermogenic Reactions to Orexin A

S¹

2014

J Psychiatry

View full text Add to dashboard Cite

This review of our literature describes the effects of many neuroleptic drugs on the sympathetic and hyperthermic reactions due to orexin A, a neuropeptide affecting body temperature and food intake by an increase in sympathetic activity. Haloperidol reduces, while clozapine and olanzapine block the hyperthermia induced by orexin A. Risperidone enhances the elevation of body temperature due to orexin A. Quetiapine delays these hyperthermic effects. The implications on human therapeutic strategies are discussed, including the involvement of orexinergic pathway in the induction of obesity, induced by these neuroleptic substances. We summarize our published data in a unique report so to emphasize the influences of these neuroleptic drugs on the control of body temperature, exerted by orexinergic system. This large vision could be also useful to address therapeutic choices.Patients with serious mental illness are at higher risk of developing metabolic abnormalities (e.g., weight gain, increased blood pressure, and glucose or lipid levels) in comparison to general population. Since the risk increases following initiation of narcoleptic therapy, it must assess carefully risks and benefits when choosing a particular antipsychotic drug.

show abstract

Section: Discussionmentioning

confidence: 99%

Neuroleptic Drugs Affect Sympathetic and Thermogenic Reactions to Orexin A

S¹

2014

J Psychiatry

View full text Add to dashboard Cite

show abstract

“…Therefore, it is reasonable to assume that obesity may also be caused by an increase in food intake (EI) resulting from reduced sympathetic activity [46], manifesting the important role of SNS in regulating both EE and EI.…”

Section: Obesity and The Sympathetic Nervous Systemmentioning

confidence: 99%

The effect of caffeine on energy balance

Harpaz

Tamir

Weinstein

et al. 2016

Journal of Basic and Clinical Physiology and Pharmacology

109

View full text Add to dashboard Cite

Abstract:The global prevalence of obesity has increased considerably in the last two decades. Obesity is caused by an imbalance between energy intake (EI) and energy expenditure (EE), and thus negative energy balance is required to bring about weight loss, which can be achieved by either decreasing EI or increasing EE. Caffeine has been found to influence the energy balance by increasing EE and decreasing EI, therefore, it can potentially be useful as a body weight regulator. Caffeine improves weight maintenance through thermogenesis, fat oxidation, and EI. The sympathetic nervous system is involved in the regulation of energy balance and lipolysis (breakdown of lipids to glycerol and free fatty acids) and the sympathetic innervation of white adipose tissue may play an important role in the regulation of total body fat. This article reviews the current knowledge on the thermogenic properties of caffeine, and its effects on appetite and EI in relation to energy balance and body weight regulation.

show abstract

“…Line bisection is a task that may be affected by different factors [13][14][15][16][17][18][19][20][21][22][23][24][66][67][68][69][70][71][72][73]. However, the factors related to the stimulus were comparable between the studies that found a leftward and those that found a rightward bisection bias.…”

Section: Rightward Bisection Bias Left Hemineglectmentioning

confidence: 99%

Asymmetries of Visuospatial Attention in Schizophrenia

Chieffi¹,

Villano²,

Iavarone³

et al. 2016

J Psychiatry

View full text Add to dashboard Cite

Journal of Psychiatry AbstractAsymmetries of visuospatial attention has long been described in hemispatial neglect, a neurological syndrome in which brain damaged patients fail to acknowledge or explore stimuli presented to the contralesional side of space. Asymmetries for spatial attention were also investigated in schizophrenia. In this review, we report the researches that, using tasks selectively employed to study visuospatial processing in neglect patients, demonstrated hemineglect-like behaviour in schizophrenia. Intriguingly, these studies produced mixed evidence. Some researches found biases towards the left hemispace suggesting a right hemineglect, others towards the right hemispace suggesting a left hemineglect. We examine the possible factors that may have contributed in producing these conflicting findings.

show abstract

Autonomic Nervous System in the Control of Energy Balance and Body Weight: Personal Contributions

Cited by 92 publications

References 36 publications

Neuroleptic Drugs Affect Sympathetic and Thermogenic Reactions to Orexin A

Neuroleptic Drugs Affect Sympathetic and Thermogenic Reactions to Orexin A

The effect of caffeine on energy balance

Asymmetries of Visuospatial Attention in Schizophrenia

Contact Info

Product

Resources

About