Au-BP7@SP nanohybrids with active motion under NIR laser irradiation can effectively enhance the temperature of tumor potentially by converting the kinetic energy to thermal energy, enhancing the killing efficiency of the tumor cells compared with Au@SP. The study provides an insight of nanohybrids' effect on photothermal treatment and opens a new avenue to cancer treatment by using self-propulsion Janus nanohybrids.

We report an assembly and transformation process of a supramolecular module, BP-KLVFF-RGD (BKR) in solution and on specific living cell surfaces for imaging and treatment. The BKR self-assembled into nanoparticles, which further transformed into nanofibers in situ induced by coordination with Ca(2+) ions.

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The process of in situ morphology transformation of the polymeric peptide (BKP) from nanoparticles to nanofibers controlled by H-bonds and hydrophobic interactions is explored. Increasing hydrophilic chain length of the molecule accelerates the morphology transformation.

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A novel medical image segmentation approach, termed as threshold-based level set approach, is presented, which combines the threshold segmentation method with the fast marching method. In this approach, the original image is firstly preprocessed by anisotropic filter in order to enhance the image edge and filter noise, and then the threshold segmentation method is used to control the diffusion coefficient of curve within the threshold set, and finally the image is segmented by using improved fast marching method (FMM). The speed function of FMM is defined based on the statistical similarity degree of the regions. The experimental results show that this approach can improve the segmentation effect and raise the segmentation speed.

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