PURPOSE: To evaluate and compare the objective and subjective outcomes between bilateral implantation of the extended depth of focus (EDOF) Mini Well intraocular lens (IOL) and the aspheric monofocal Mini-4-Ready IOL (both SIFI S.p.A., Catania, Italy). METHODS: This prospective comparative study included 25 patients (50 eyes) bilaterally implanted with an EDOF Mini Well IOL (EDOF group) and 25 patients (50 eyes) bilaterally implanted with a Mini-4-Ready IOL (monofocal group). Three-month follow-up data included corrected and uncorrected distance visual acuity at 4 m and 80, 67, and 40 cm. Defocus curves, subjective and objective contrast sensitivity, and objective optical quality (modulation transfer function cutoff and Strehl ratio calculated with Optical Quality Analysis System [OQAS]; Visiometrics SL, Terrassa, Spain), halometry, and reading performance were measured. Subjective visual quality was evaluated based on National Eye Institute Refractive Error Quality of Life Instrument 42 (NEI RQL-42) scores. RESULTS: Postoperative uncorrected and corrected monocular and binocular intermediate and near visual acuity was significantly better in the EDOF group ( P < .001). No differences were observed for distance visual acuity ( P ⩾ .312). Defocus curve outcomes for myopic values were better in the EDOF group ( P < .001). No significant differences were found in hyperopic (obtained in steps of +0.50 diopters [D] from emmetropia to 1.50 D) values ( P ⩾ .095), contrast sensitivity curves ( P ⩾ .087), or OQAS outcomes ( P ⩾ .138). Halometric values were significantly better in the monofocal group ( P < .05). There was a correlation between mean keratometry values and intermediate/near visual acuity. Significantly better NEI RQL-42 subscale scores for near vision, far vision, activity limitations, glare, dependence on correction, and suboptimal correction were noted in the EDOF group ( P < .05). CONCLUSIONS: Intermediate and near visual acuity was better after EDOF IOL than after aspheric monofocal IOL implantation while maintaining similar levels of visual quality, except for halo perception. [ J Refract Surg . 2020;36(4):214–222.]

Purpose: To evaluate the safety and efficacy of double compared to single intraluminal suture stenting in reducing early postoperative hypertensive spikes (HS) and hypotony after Baerveldt glaucoma implant surgery. Methods: For this retrospective study, we reviewed the medical charts of 60 patients (60 eyes) who underwent Baerveldt drainage device surgery between 2017 and 2019. Two groups were formed according to whether a single suture stent was placed within the tube (5-0 polypropylene, 30 eyes, group 1) or a double suture (5-0 and 6-0 polypropylene, 30 eyes, group 2). Intraocular pressure (IOP) was measured at baseline, at 6 h, and on postoperative days 1, 2, 5, 7, 14, 21, 30, 60, 90, 180. The occurrence of HS (IOP ⩾ 30 mmHg), anterior chamber reformation, decompressive paracentesis, anti-glaucoma medication, and adverse events were recorded. Results: There was a greater decrease in IOP from baseline at days 1, 2, and 21 ( p < 0.05) and number of HS at 6 h ( p = 0.006) and postoperative day 1 ( p < 0.001) in group 2. The mean number of decompressive paracentesis, anterior chamber reformation procedures, and topical anti-glaucoma medications was the same in both groups; the need for oral acetazolamide was significantly lower in group 2 at days 1, 21, and 30 ( p < 0.05). Conclusions: While both stenting methods provide a gradual, controlled decrease in IOP, the double stenting technique was associated with a sooner and greater postoperative reduction in IOP and a good safety profile thanks to fewer HS in the early postoperative period and less need for oral acetazolamide.

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PURPOSE: To compare the objective and subjective outcomes between the extended depth of focus (EDOF) Mini Well intraocular lens (IOL) and the aspheric monofocal Mini-4-Ready IOL (both SIFI S.p.A.) in patients with high myopia. METHODS: In this prospective comparative study, 40 patients with high myopia (axial length ≥ 26 mm) were enrolled: 20 patients were bilaterally implanted with the EDOF Mini Well IOL (EDOF group) and 20 patients were bilaterally implanted with the Mini-4-Ready IOL (monofocal group). Three-month follow-up data included corrected and uncorrected distance visual acuity at 4 m and 80, 67, and 40 cm, defocus curves, subjective and objective contrast sensitivity, objective optical quality (calculated with Optical Quality Analysis System; Visiometrics SL), halometry, and reading performance. Subjective visual quality was evaluated with National Eye Institute Refractive Error Quality of Life Instrument 42 scores. RESULTS: All visual acuities were significantly better in the EDOF group ( P ⩽ .04) except monocular and binocular uncorrected and corrected distance visual acuities for distance ( P ≥ .50). Defocus curves for myopic and hyperopic values were better in the EDOF group ( P ⩽ .05), apart from +0.50 to −0.50 D ( P ≥ .16). Contrast sensitivity curves was worse in the EDOF group in the mesopic-with-glare condition ( P ⩽ .04). No differences were found in halometric values ( P ≥ .15) and OQAS outcomes ( P ≥ .47). National Eye Institute Refractive Error Quality of Life Instrument 42 subscale scores were better for expectation, near vision, activity limitations, and dependence on correction in the EDOF group ( P ⩽ .04). CONCLUSIONS: Intermediate and near visual acuities were better in the EDOF group than in the monofocal group, with a comparable visual quality index between groups. [ J Refract Surg . 2022;38(3):158–166.]

Purpose: To evaluate the efficacy and safety of micropulse transscleral cyclophotocoagulation (MP-CPC) as a therapeutic option for severe glaucoma and to compare two different durations of treatment.Methods: Retrospective observational study of 40 eyes of 40 patients affected by different types of glaucoma treated with micropulse transscleral cyclophotocoagulation at 2000 mW for a duration of either 90 seconds per hemisphere (20 patients) or 80 seconds per hemisphere (20 patients) at 31.3% duty cycle. As main outcomes were evaluated postoperative intraocular pressure (IOP) and topical drugs reduction. Complications of the treatment and a comparative analysis of 2 different durations as secondary outcomes.Results: MP-CPC was successful in 26 patients (65%) and achieved a significant IOP reduction of 34.4% (p<0.001) after 12 months. The mean number of topical antiglaucoma medications has not statistically decreased from baseline (3.4 ± 1.0) to 12 months (3.2 ± 0.8). One case of IOP spike (>35 mmHg) and 1 case of cystoid macular oedema were the only complications detected. The comparison between the 90 seconds per hemisphere and the 80 seconds per hemisphere group did not show any statistically significant difference in IOP reduction, topical medication burden and incidence of complications.Conclusion: MP-CPC demonstrated to be an effective and safe treatment in lowering the IOP. Glaucoma topical medications did not significantly reduce. From our comparative analysis reducing the duration of treatment seems not to affect the outcomes.