Objective: To analyze and compare perinatal outcomes of pregnant adolescent women and pregnant women in later age (between 20 and 34 years old) from data of a Live Born Information System. Methods: A cross-sectional study was carried out with data collected retrospectively of 18,009 live born infants from consults of data of a Live Born Information System. Registers of live born infants were distributed in three groups: group I (adolescents) -10 to 19 years old; group II -20 to 34 years old; and group III (later age) -35 years or older. Results: Findings showed that perinatal risks were related to prematurity (OR 1,35) and five-minute Apgar scores of less than seven (OR 1,44) among infants born to adolescent mothers. Conclusion: Results pointed out high indexes of preterm birth in low-birth-weight infants and five-minute Apgar scores of less than seven in pregnancies that occurred in adolescents and in women 35 years and older. ResumoObjetivo: Analisar e comparar os resultados perinatais de gestantes adolescentes e em idade tardia com mulheres entre 20 a 34 anos, a partir dos dados do Sistema de Informação de Nascidos Vivos. Métodos: Foi realizado um estudo transversal, com coleta de dados retrospectiva de 18009 nascidos vivos a partir de consultas aos dados do Sistema de Informação de Nascidos Vivos. Os registros dos nascidos vivos foram distribuídos em três grupos: grupo I (adolescentes) -10 a 19 anos; grupo II -20 a 34 anos e grupo III (idade tardia) -35 anos ou mais. Resultados: Os resultados mostraram riscos perinatais relacionados à prematuridade (OR 1,35) e Apgar quinto minuto menor que sete (OR 1,44) em mães adolescentes. O baixo peso ao nascer apresentou risco de 1,22 e 1,24 vezes entre as gestantes do grupo I e III. Conclusão: Os resultados apontaram elevados índices de nascimento pré-termo, baixo peso ao nascer e Apgar no quinto minuto menor que sete nas gestações ocorridas em adolescentes e em mulheres com idade igual ou superior aos 35 anos.

IntroductionBreast cancer is the most common cause of cancer death among women.ObjectiveThe objective of this study was to analyze time trends in overall mortality from breast cancer in Brazil, Brazilian regions and States.MethodsThis is an exploratory study, of the time series of deaths from breast cancer contained in the Mortality Information System (SIM), of women living in Brazil, Brazilian regions and States, from 1996 to 2013. For the trend analysis, the polynomial regression model was used, and a significant trend was considered when the estimated model obtained a p value <0.05.ResultsThere was a tendency of increased mortality from breast cancer in Brazilian women (average increase of 0.18 per year; p <0.001), with regional differences, particularly in the age group 20–49 years (0.07 per year; p <0.001). The age group 50–69 years remained constant but had high average rates (37.14).ConclusionMore effective planning is needed to focus on the different scenarios of the Brazilian regions. Screening strategies for the incidence and mortality from breast cancer must also be rethought according to age group in the country.

BackgroundThe menopause is associated with a tendency to gain weight. Several alterations in fat deposits occur, leading to changes in the distribution of body fat. There are strong indications that, in middle age, obesity is associated with increased mortality. This study set out to determine the factors associated with the prevalence of overweight and abdominal obesity in postmenopausal women in a population-based study in Brazil.MethodsThe sample included 456 women, aged 45–69 years, residing in the urban area of Maringa, Parana. Systematic sampling, with a probability proportional to the size of the census sector, was performed. Behavioral, economic, and sociodemographic data were collected, and body mass index (BMI) and waist circumference (WC) were determined.ResultsAccording to BMI criteria (≥25.0 kg/m2), 72.6% of the women were overweight, and according to WC (≥88 cm), 63.6% had abdominal obesity. Based on logistic regression analysis, the factors that were most closely associated with overweight were: having three or more children (odds ratio (OR): 1.78; 95% confidence interval (CI): 1.06–3.00); and not taking hormone replacement therapy (OR: 1.69; 95% CI: 1.06–2.63). The prevalence of abdominal obesity was positively associated with greater parity (OR: 1.34, 95% CI: 1.05–1.72) and age older than 65 years (OR: 1.50; 95% CI: 1.03–2.19).ConclusionsThis study found that the prevalences of overweight and abdominal obesity were higher for postmenopausal women who had three or more children. Age over 65 years was also a risk factor for abdominal obesity and no use of hormonal replacement therapy was a risk factor for overweight.

Objective: The objective of this study was to determine the prevalence of metabolic syndrome (MS) and its components among pre-and postmenopausal women, as well as the association between menopausal status and MS. Materials and methods: A retrospective study was conducted at a reference cardiology outpatient clinic in a city located in Northwestern Paraná State, Brazil. A total of 958 medical records of symptomatic climacteric women evaluated between 2010 and 2014 were analyzed. The study consisted of two groups: pre-and post-menopausal women. MS was characterized according to the criteria of the National Cholesterol Education Program's Adult Treatment Panel III -NCEP-ATP III-2005. Results: MS was observed in 18.5% of the total study population; 9.4% of the premenopausal women and 22.2% of the postmenopausal women displayed MS, corresponding to a relative risk of 2.75. In addition, the frequency of MS increased with age. Regarding the components of MS, postmenopausal women were more likely to have high density lipoprotein (HDL-C) levels < 50 mg/dL; systolic blood pressure (SBP) values ≥ 130 mmHg or diastolic blood pressure (DBP) values ≥ 85 mmHg; and fasting glucose levels ≥ 100 mg/dL. Conclusion: MS was more prevalent among postmenopausal women than among premenopausal women. Arch Endocrinol Metab. 2017;61(2):160-6.

RESUMOObjetivou-se investigar os resultados perinatais nos extremos da vida reprodutiva e verificar os fatores de risco para o baixo peso ao nascer. Trata-se de um estudo retrospectivo dos partos ocorridos no município de Sarandi, Paraná, no ano de 2008, a partir de consultas aos dados do Sistema de Informação de Nascidos Vivos. As 331 gestantes foram subdivididas em dois grupos: adolescentes (10-19 anos) e tardias (35 anos ou mais). As taxas de parto cesáreo foram significativamente maiores (66,1%) nas gestantes com 35 anos ou mais do que nas adolescentes (26,8%). Quanto aos fatores de risco para o baixo peso ao nascer, observou-se que este esteve fortemente associado com prematuridade e o estado civil. Os resultados perinatais das gestantes com 35 anos ou mais não apresentaram diferença significativa quando comparados aos resultados das adolescentes, confirmando a ocorrên-cia de resultados adversos nos dois extremos da vida reprodutiva, exceto pela ocorrência de parto cesáreo.Descritores: Idade materna. Resultado da gravidez. Peso ao nascer. Fatores de risco. RESUMEN El objetivo fue investigar los resultados perinatales en los extremos de la vida reproductiva y verificar los factores de riesgo de bajo peso al nacer. Se trata de un estudio retrospectivo de partos ocurridos en Municipio de

Objective: To identify the presence of depressive symptoms in elderly enrolled in a control program for hypertension and diabetes mellitus in a municipality of northwestern Paraná. Methods: A descriptive, transversal study conducted in basic health units in Sarandi -PR (Brazil), with 100 elderly registered in the Programa Hiperdia [Hyperday program]. A mental health section of the questionnaire, Brazil Old Age Schedule (BOAS), was used. The Mann-Whitney and Chi-Square tests were used to analyze the association between depressive symptoms and sociodemographic characteristics and nutritional status. Results: The majority of the elderly were female (82.0%). The prevalence of depressive symptoms was 30.0%, of which 20.0% were classified as major depression. The depressive symptoms were more frequent in those who were: women (31.7%); 80 years of age or older (33.3%); without education (39.1%); living alone (43.7%); underweight (33.3%) or obese (32.5%). Conclusion: The family health strategy teams need to be attentive to the presence of depressive symptoms in the elderly , especially in those who are already attending established support groups. Keywords: Aged; Depression; Hypertension; Diabetes mellitus; Mental health; Public health RESUMO Objetivo: Identificar a presença de sintomas depressivos em idosos inscritos no Programa de controle de hipertensão arterial e diabetes mellitus em um município do Noroeste do Paraná. Métodos: Estudo descritivo transversal, realizado nas unidades básicas de saúde de Sarandi -PR, com 100 idosos cadastrados no Programa Hiperdia. A seção de saúde mental do questionário Brazil Old Age Schedule (BOAS) foi usada. Os testes Mann-Whitney e Qui-quadrado foram empregados para analisar a associação entre sintomas de depressão e características sociodemográficas e estado nutricional. Resultados: A maioria dos idosos era do sexo feminino (82,0%). A prevalência de sintomas depressivos foi de 30,0%, dos quais 20,0% classificados como depressão maior. Os sintomas depressivos foram mais frequentes nas mulheres (31,7%); em idosos com 80 anos e mais (33,3%); sem nenhuma escolaridade (39,1%), que moravam só (43,7%) e que apresentavam baixo peso (33,3%) ou obesidade (32,5%). Conclusão: As equipes da estratégia saúde da família devem estar atentas para a presença de sintomas depressivos em idosos, sobretudo aqueles que pertencem aos grupos de convivência já instalados. Descritores: Idoso; Depressão; Hipertensão; Diabetes mellitus; Saúde mental; Saúde Pública RESUMEN Objetivo: Identificar la presencia de síntomas depresivos en ancianos inscritos en el Programa de control de hipertensión arterial y diabetes mellitus en un municipio del Nor oeste de Paraná. Métodos: Estudio descriptivo transversal, realizado en las unidades básicas de salud de Sarandi -PR, con 100 ancianos registrados en el Programa Hiperdia. Fue usada la sección de salud mental del cuestionario Brazil Old Age Schedule (BOAS). Los tests Mann-Whitney y chicuadrado fueron empleados para analizar la asociación entre síntomas de depres...

BackgroundHuman Papillomavirus (HPV) infection is particularly burdensome for women infected with human immunodeficiency virus (HIV), which increases their risk of developing cervical lesions and cancer (CC). We conducted a molecular study of the distribution of cervical HPV genotypes and the risk factors for this infection in HIV-infected Brazilian women.FindingsCervical and endocervical samples for Papanicolaou screening and HPV detection were collected from 178 HIV-infected women using highly active antiretroviral therapy (HAART) of Maringá city/Brazil. Risk factors were assessed using a standardized questionnaire, and the data regarding to HIV infection from medical records. HPV was detected by polymerase chain reaction (PCR), and genotyping using PCR-restriction fragment length polymorphism analysis. HIV infection was well controlled, but women with a current CD4+ T lymphocyte count between 200–350 cells/mm3 (37.6%) had a two-fold greater risk of HPV infection than those with > 350 cells/mm3 (26.4%). HPV was associated with parity ≥3, hormonal contraceptive use and current smoker. HPV infection occurred with high frequency (46.6%) but a low frequency of cervical abnormalities was detected (7.30%), mainly low-grade squamous intraephitelial cervical lesions (LSIL) (84.6%). A high frequency of multiple HPV infections was detected (23.0%), and the most frequent HPV genotype was HPV-72 (6.7%), followed by −16, -31 and -51 (6.14% each).ConclusionsWe showed that HAART use does not protect HIV-infected women from HPV, but appear to exert some protection against cervical lesions development. This study provides other important information about risk factors and cervical HPV in HIV-infected women, which can contribute to planning protocols.

Objective:To identify the factors associated with intra-hospital neonatal mortality based on the individual characteristics of at-risk pregnant mothers, delivery and newborns. Method: This was a cross-sectional epidemiological study of live newborns delivered by women attended at the high-risk outpatient unit of a philanthropic hospital in Maringá, Paraná, Brazil between September 2012 and September 2013. Results: Six hundred and eighty-eight women participated in the study. The neonatal mortality coefficient found was 17.7/1,000 live births, most in the early neonatal phase. Premature labor, fetal malformation and multiple gestations were associated with neonatal death. Premature, very low birth weight newborns and those with an Apgar score of less than seven, five minutes after birth were at high risk of death. Conclusion: Identifying risk factors can help plan actions to consolidate the perinatal network. Specific programs should be incentivized in other countries, in the search for significant perinatal results such as reducing neonatal mortality. . If we break down infant mortality by age, worldwide, neonatal (0 to 27 days) deaths account for 44% of all deaths among children under the age of five (3) . In Brazil this component is even larger, and can be as high as 70% in all regions (2) , with 11.2 deaths per thousand live births between 2011 and 2012 (4) . In the state of Paraná, neonatal deaths dropped from 2,426 in 1996 to 1,279 in 2014 (94.8% less). However, in spite of all the progress made, 71.8% of infant deaths in 2014 were in the neonatal period (5) . According to the Report on Levels and Trends in Infant Mortality (Relatório de Níveis e Tendência em Mortalidade Infantil), the main goal is to reduce mortality in the neonatal period, which is where most infant deaths occur (1) . To reduce maternal and infant mortality, and the high percentage of avoidable deaths, in 2012 a public policy for prenatal care and for the care of newborns at risk was created in Paraná. It focuses on early detection of pregnant women at risk, their prenatal care, risk stratification of mothers and infants, specialized ambulatory care for pregnant women and infants (under the age of one) at risk, and ensured delivery via a system that is linked to the hospital (6) . Numerous studies have attempted to analyze the causes of neonatal deaths. Studies show a strong link between neonatal deaths and maternal and infant life conditions and health, economic situation, and access to healthcare, and to biological conditions such as gestational age, weight at birth and Apgar index (7) . We also call attention to the risk in the current and previous pregnancy (prior stillbirth, premature or low birth weight infants), the movement of the pregnant woman to delivery and women giving birth to low-weight babies (< 1,500 grams) in hospitals not equipped with a Neonatal Intensive Care Unit (NICU) (4) . Studies show that among newborns in NICU, Cesarean birth, failure to use steroids, pre-eclampsia, oligohydramnios, <2,500 grams ...