RESUMOEm pesquisa sobre a prevalência de infecção pelos vírus das hepatites na sede do Município de Juruti, oeste do Estado do Pará, Brasil, realizada entre fevereiro de 2007 e abril de 2008, foi demonstrada a necessidade de ampliar estudos de soroprevalência baseados em comunidades. Objetivando atender essa necessidade, o estudo foi ampliado para definir a prevalência das infecções pelos vírus das hepatites A (VHA), B (VHB), C (VHC), D (VHD) e E (VHE), entre fevereiro de 2007 e novembro de 2010, envolvendo amostras de soro de indivíduos residentes na sede e nas localidades rurais Café Torrado, Jauari, Nova Galiléia, Vila Muirapinima e Lago Jará, do Município de Juruti, com estimativa de população de 52.755 habitantes em 2014. Tais amostras foram submetidas à análise dos marcadores sorológicos das hepatites A, B, C, D e E, por técnica imunoenzimática. Nas amostras positivas para VHB e VHC, foram realizadas pesquisas para detecção do VHB-DNA e VHC-RNA.
Introduction: We evaluated the anti-hepatitis E virus (HEV) antibody prevalence and HEV-RNA in archived serum samples of non-A-C hepatitis, or suspected cases of HEV infection from the Eastern Brazilian Amazon from 1993 to 2014. Methods: Serum samples (n = 318) were tested using ELISA and immunoblotting, and screened for HEV-RNA by RT-qPCR. Results: Anti-HEV IgM and IgG were detected in 3.4% (11/318) and 5.9% (19/318) of the samples, respectively. All samples were HEV-RNA negative. Conclusions: HEV was detected at a low prevalence. Broader serological and molecular evaluation of HEV infection in the Amazon region should be carried out. De Souza AJS et al. -HEV infection in suspected cases from the Amazon 15. Passos-Castilho AM, de Sena A, Reinaldo MR, Granato CFH. Hepatitis E virus infection in Brazil: results of laboratorybased surveillance from 1998 to 2013. Rev Soc Bras Med Trop. 2015;48(4):468-70. De Souza AJS et al. -HEV infection in suspected cases from the Amazon OPEN ACCESS https://creativecommons.org/licenses/by/4.0/
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