Paper discusses the career opportunities of the management's personnel reserve, considering theorists and practitioners basic issues on organizations' abilities to ensure reservists' career growth. The study analyzes staff opportunities to get into the management's personnel reserve and employees' expectations on the management's personnel reserve. Using questionnaires we revealed that it is difficult to get into the management's personnel reserve, the most of the respondents (62%) has no such opportunity. As the most valuable career opportunities respondents consider professional growth (58%) and personal managerial skills development (55%). They also hopes on the clarification of personal development trajectory, career advancement and acquisition of new relationships that are enable to facilitate further promotion. Gender approach proved men priority in sociability. While women in the personnel reserve are looking for more independence. The age aspect also influences the reservists' ability. Despite some advantages of youth, managerial sphere highly needed for experienced staff at the age of 31 -40 years. Significantly reduced career opportunities are typical for employees older than 50. Based on the research, it was concluded that the career opportunities of the management's reserve should not be limited -all employees' potential has to be aimed at organization competitiveness increasing and takes into account the reservists' gender and age characteristics.

In this article we have examined main theoretical approaches to time-management and practice of its development in education. Authors have demonstrated the need to focusing on theory and practice of time-management in Russia considering quickly-changing processes in the world and deficit of time. The various methodologies of time-management including tools, technics and methods were analyzed. Authors have showed stages of practical appliance of self-management. We have presented results of research about the role of student in time-management to improve the efficiency of educational process. The data, fixing amount of time that students spend on accomplishing different tasks, personal records, time of rest, analyzing statistical data were collecting by using timing. Analysis let us to define the structure of student`s life to expose priorities, the most important, effortful and time-consuming tasks (using the tool of pair comparison). Pair comparison made it possible to compare and follow the way of changes in the structure of time management of students, based on instructive conclusions from the analysis of the first week of studies. Using polls we exposed the opinions of students about their health, dynamics of changes, negatively impacting factors etc. During research we have found the ways student waste their time, we have designed methods to overcome procrastination, we have developed ways to study using personal syllabus, video projects. Using the results of the poll we have formulated basic principles of introduction of time-management into student's life which are goal-setting, defining of priorities, timeliness, verification, balance. Keywords: time-management, methods of using of time, self-management, tool of timekeeping, timing, technique the matrix of Eisenhower, ABC-analysis, students time-management, sources of procrastination, traps of time, time reserves www.ccsenet.org/ass

To continue progress in the treatment of cardiovascular disease, there is a need to improve the overall understanding of the processes that contribute to the pathogenesis of cardiovascular disease (CVD). Exploring the role of gut microbiota in various heart diseases is a topic of great interest since it is not so easy to find such reliable connections despite the fact that microbiota undoubtedly affect all body systems. The present study was conducted to investigate the composition of gut microbiota in patients with atherosclerotic cardiovascular disease (ASCVD) and heart failure syndromes with reduced ejection fraction (HFrEF) and HF with preserved EF (HFpEF), and to compare these results with the microbiota of individuals without those diseases (control group). Fecal microbiota were evaluated by three methods: living organisms were determined using bacterial cultures, total DNA taxonomic composition was estimated by next generation sequencing (NGS) of 16S rRNA gene (V3–V4) and quantitative assessment of several taxa was performed using qPCR (quantitative polymerase chain reaction). Regarding the bacterial culture method, all disease groups demonstrated a decrease in abundance of Enterococcus faecium and Enterococcus faecalis in comparison to the control group. The HFrEF group was characterized by an increased abundance of Streptococcus sanguinus and Streptococcus parasanguinis. NGS analysis was conducted at the family level. No significant differences between patient’s groups were observed in alpha-diversity indices (Shannon, Faith, Pielou, Chao1, Simpson, and Strong) with the exception of the Faith index for the HFrEF and control groups. Erysipelotrichaceae were significantly increased in all three groups; Streptococcaceae and Lactobacillaceae were significantly increased in ASCVD and HFrEF groups. These observations were indirectly confirmed with the culture method: two species of Streptococcus were significantly increased in the HFrEF group and Lactobacillus plantarum was significantly increased in the ASCVD group. The latter observation was also confirmed with qPCR of Lactobacillus sp. Acidaminococcaceae and Odoribacteraceae were significantly decreased in the ASCVD and HFrEF groups. Participants from the HFpEF group showed the least difference compared to the control group in all three study methods. The patterns found expand the knowledge base on possible correlations of gut microbiota with cardiovascular diseases. The similarities and differences in conclusions obtained by the three methods of this study demonstrate the need for a comprehensive approach to the analysis of microbiota.

The purpose of this study was to determine the impact of institutional changes on the working environment and health of employees working in the Centralized dean's office and students, their motivation and training duties. Research methods included observation, interviews, questionnaires and statistical approaches. Research results suggest that formation of the learning environment is most strongly influenced by a number of factors, such as institutional changes, infrastructural developments of the University managerial qualities of employees, their cooperation level with students and above all -motivation for creative and conscientious work, individual and career development conditions, socio-psychological climate and management style. The study found the following dependence of students: combination of work and study duties increased the frequency of stress cases and ill health, but increased motivation for the development of self-organization.

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The main approaches for development of assessment technology of higher education institution's administrative personnel are considered in this article. Alongside with it the following is defined: purposes, formation principles, indicators and criteria of the assessment system, rating scale, the procedure and order of assessment process of higher education institution's administrative personnel personal performance. Criteria of an assessment of personal efficiency of employees of higher education institution are considered in case the employee significantly exceeds expectations ("image" of a perfect employee), exceeds expectations, meets expectations, needs an improvement and doesn't meet expectations ("image" of the bad employee). The procedure of payments of the individual size of an award of the worker proceeding from the received assessment is shown.Keywords: procedure of personnel assessment, system of higher education institution's assessment, balanced system of indicators, jobs grading, assessment technology of higher education institution's administrative personnel personal performance

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