There are still few reports of secondary metabolites from lichens Usnea sp. as an antidiabetic agent. Based on data from the International Diabetes Federation 15) , the prevalence of global diabetes is expected to increase by 552 million by 2030. Data from the World Health Organization (WHO) 16) also reports that diabetes mellitus is the seventhlargest cause of death. One of the essential therapeutic methods for reducing plasma glucose levels is to inhibit α-glucosidase activity 17−19) . Several previous studies have reported the potential of lichen exploration as a good antidiabetic agent. The α-amylase inhibition test which has shown a positive potency there are 22 types of lichen, such us Ramalina conduplicans,
Exploration of lichen natural compounds has attracted a lot of attention from researchers as potential medicinal raw materials because chemical compounds contained in lichen have many properties. The potential for developing secondary metabolite compounds of lichen has become a trend for various benefits, for example, in cosmetics, agriculture, health, and food. Lichen Teloschistes flavicans was a concern to study because there were not many reports of secondary metabolites that have antimicrobial activity. The research objective was to examine antimicrobial activity using 3-[1’-(2”,3”-dihydroxy-phenyl)-propyl]-7hydroxy-chroman-4-one compound from lichen Teloschistes flavicans. The antimicrobial activity test was a well diffusion method. Bioactivity was determined by calculating the clear zone formed around the well. Antimicrobial activity testing indicated the inhibition of bacterial growth at a concentration of 500 ppm and 1000 ppm with the respective inhibition zones namely E. coli (10-11 mm), S. Typhi (2-5 mm), K. pneumoniae (11-13 mm), and S. aureus (10-13 mm). Also, B. cereus bacteria and C. albicans fungi were only inhibited at a concentration of 1000 ppm with an inhibition zone of 6 mm each. This research provides scientific knowledge about the potential development of lichen T. Flavicans as an antimicrobial.
Potensi secara ekonomi pada sistem pembesaran tersebut perlu dikaji untuk menentukan sistem pembesaran apakah layak dikembangkan melalui metode penelitian deskriftif kuantitatif dengan menggunakan sumber data primer dan sekunder, serta teknik pengambilan data riset berdasarkan observasi, studi literatur, dan partisipasi aktif. Hasil penelitian ini menunjukkan bahwa analisis kelayakan finansial pada pembesaran udang vanname (Litopenaeus vannamei) sistem intensif dengan penerimaan sebesar Rp 2.805.950.188 pertahun, nilai pendapatan sebesar Rp 1.211.324.360 pertahun. Hasil BEP Rupiah sebesar Rp 969.012.008 dalam 1 tahun. Hasil BEP Unit sebesar 11.530 Kg dalam 1 tahun. Hasil R/C Ratio Rp 1.76. Hasil analisis ROI sebesar 48%. Payback Period 2 tahun 18 hari artinya usaha ini sangat layak dikembangkan.
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