Infinite dilution activity coefficients (γ ∞) were measured at 298 K for 9 different aliphatic hydrocarbons (alkanes, cycloalkanes, alkenes), 7 different aromatic compounds (benzene, alkylbenzenes, halobenzenes), and for 1,2-dichloropropane, dichloromethane, acetone, acetonitrile, tetrahydrofuran, 1,4-dioxane and 2-propanol dissolved in both 2-propoxyethanol and 2-isopropoxyethanol at 298 K using a headspace gas chromatographic method. As part of the experimental study solubilities of 18 and 20 crystalline organic nonelectrolyte solutes were determined in 2-propoxyethanol and 2-isopropoxyethanol, respectively, at 298 K using a uv/visible spectrophotometric method. The experimental values were converted to gas-toalkoxyethanol, water-to-alkoxyethanol partition coefficients, and molar solubility ratios using standard thermodynamic relationships. Abraham model correlations for solute transfer into both alkoxyethanols were derived from the calculated solubility ratios and partition coefficients. The
Experimental infinite dilution activity coefficient data, gas-to-liquid partition coefficient data, and solubility data have been combined from the published literature for neutral organic molecules and inert gases dissolved in anhydrous acetic acid. The compiled experimental data were transformed into molar solubility ratios, water-to-acetic acid (P) and gas-to-acetic acid (K) using standard thermodynamic relationships. The derived Abraham model correlations described the observed solubility and partition coefficient data of neutral organic compounds to within 0.18 log units (or less). Our analysis further showed that acetic acid solvent has considerable hydrogen-bond acidity, in agreement with the proposed linear structure for the solvent, and in terms of solubility related properties is not an unusual solvent at all.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.