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Objective: To determine the increase of fibroblast cell number in the rat (Rattus norvegicus) gingival wound after the application of moringa (Moringa oleifera Lam) fruit oil. Material and Methods: This study was an experimental post-test control group design using 18 male Wistar rats (Rattus norvegicus) that was divided into three groups. The sample was previously incised with a length of 4 mm using scalpel 15. Group 1 was applied with moringa fruit oil, group 2 was given aspirin, and group 3 was given at 0.5% CMC. The application was carried out every 24 hours, then on the third and seventh day, the rats were euthanized for histological preparations and then observed under the electric microscope. The length of the lesion was measured on the first, third, and seventh days. The fibroblast was then observed by counting the number of fibroblast cells per field of view using an Olympus C-21 microscope with an Optilab Advances camera with a 40x, 100x magnification, and 400x. The data were processed and analyzed using the SPSS Version 21 program. This study used a t-test to see the differences between the treatment group and the control group, and the Least Significantly Difference (LSD) test was used to see the size of the difference. Results: This study showed a significant increase in the number of fibroblasts in rat gingival mucosa on the third and seventh days. Conclusion: Moringa (Moringa oleifera Lam) fruit oil affects increasing the number of fibroblasts on the rat gingival mucosa (Rattus norvegicus).

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The aim of this study was to determine the comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptideamorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Material and Methods: This study was an experimental laboratory with cross sectional design. Study sample was 15 maxillary central incisors that were applied with 35% hydrogen peroxide for 2 hours, then assessed with Energy Dispersive Spectroscopy (EDS). Samples were divided into 3 groups: 5 samples were applied using blood clam (anadara granosa) shell paste, 5 samples using shrimp shell paste and 5 samples were applied using CPP-ACP paste every 8 hours for 14 consecutive days then checked with EDS. Data analysis using SPSS test independent t-test to see comparison of blood clam (anadara granosa) shell paste, shrimp (litopenaeus vannamei) shell paste and casein phosphopeptide-amorphus calcium phosphate (CPP-ACP) paste as teeth remineralization material. Results: The result of this study showed P> 0.05 which means there was no significant difference between blood clam shell paste, shrimp shell paste and CPP-ACP mineral composition. Conclusion: Blood clam shell paste and shrimp shell paste has an effective value to be used as tooth remineralization material.

Objective: This study was conducted to determine the effect of COVID-19 infection on the manifestations that arise in the oral environment. Methods : This study was conducted in the form of a literature review by collecting secondary data from online scientific article databases, such as PubMed, Google Scholar, and Science Direct. Results: There are various oral manifestations of COVID-19. The most common oral manifestations were xerostomia, impaired taste, burning sensation, and oral/dental pain. Conclusion : COVID-19 can cause manifestations in the oral environment which generally occur as early symptoms or in the acute phase of COVID-19.

The aim of analyze and improve the service innovation at Hasanuddin University Dental and Oral Hospital through the use of the knowledge management system. Material and Methods: The instrument used in data collection was a questionnaire. There are two variables in this study, namely the independent variable is knowledge generation, knowledge storage, knowledge diffusion, knowledge application and the dependent variable is service innovation. Results: An effect knowledge generation on increasing service innovation (p = 0.000) with an R coefficient value square of 0.392, there was an effect of knowledge storage on increasing service innovation.(p = 0.000) with an R coefficient value square of 0.285 there is an effect of knowledge diffusion on increasing service innovation (p = 0.000) with an R coefficient value of 0.374, and there is an effect of knowledge application on increasing service innovation (p=0.000) with an R coefficient value. amounting to 0.176. It is recommended that the hospital management pay attention to and optimize the knowledge application at the Hasanuddin University Dental and Oral Hospital. Conclusion: This study is that there is an effect of knowledge generation, knowledge storage, knowledge diffusion, and knowledge application on improving service innovation at

Introduction: Oral health in the elderly is usually worse than the general population and its can increase the incidence of edentulous and tooth loss. Studies show that a reduction in the number of teeth and users of complete dentures causing the ability to chew is significantly to be less efficient and have an impact on general health. The lack of chewing ability is at risk of causing cognitive impairment. Cognitive impairment in the elderly is an early clinical sign of dementia. A number of studies have reported that individual with cognitive impairments especially those involving memory problems are more likely to develop dementia compared to normal people. Objective: This literature review discusses the relationship between oral health such as tooth loss, impaired chewing ability, and in relation to cognitive impairment that can increase the risk of dementia.