AIM:In our study, we investigated the levels of glutamic acid decarboxylase antibody (anti-GAD), islet cell antibody (ICA), thyroperoxidase antibody (anti-TPO), thyroglobulin antibody (anti-TG), antinuclear antibodies (FANA), antibodies to double-stranded DNA (anti-ds DNA), antibody to Sjögren syndrome A antigen (anti-SSA), antibody to Sjögren syndrome B antigen (anti-SSB), Smith antibody (anti-Sm), smooth muscle antibodies (ASMA), and antimitochondrial antibody liver-kidney microsome (AMA-LKM) in patients with celiac disease as compared to healthy controls and autoimmune hypothyroid patients.MATERIALS AND METHODS:A total of 31 patients with celiac disease, 34 patients with autoimmune hypothyroidism and 29 healthy subjects were included in this study. Anti-SSA, anti-SSB, anti-Sm, anti-ds DNA, anti-GAD, anti-TPO and anti-TG were studied by Enzyme-Linked Immunosorbent Assay (ELISA), and AMA-LKM, ASMA, ANA and ICA were studied by immunofluorescence. Clinical data and the results of free thyroxine-thyroid stimulating hormone (FT4-TSH) were collected from the patients’ files by retrospective analysis. SPSS ver 13.0 was used for data analysis, and the χ2 method was used for comparisons within groups.RESULTS:The frequency of anti-SSA, anti-SSB, anti-GAD, anti-Sm, anti-ds DNA, AMA-LKM, ASMA, ANA and ICA were not significantly different between the groups. Levels of anti-TPO and anti-TG antibodies were found to be significantly higher (<0.001) in autoimmune hypothyroid patients when compared with other groups.CONCLUSION:In previous studies, an increased frequency of autoimmune diseases of other systems has been reported in patients with celiac disease. We found that the frequency of autoimmune antibodies specific for other autoimmune diseases was not higher in celiac disease.
BACKGROUND: Social isolation required by the pandemic has led to some changes in individuals’ eating and lifestyle habits. OBJECTIVE: This study aimed to examine the change in nutrition and lifestyle habits of Turkish people during the COVID-19 outbreak and investigate the effects of individuals’ attitudes to healthy eating on this change. METHOD: At the beginning of the pandemic, individuals over the age of 18 participated in this cross-sectional study using an online questionnaire. Demographic information (age, gender, education level, place of residence and occupation), anthropometric data (reported weight and height); nutritional behavior information (number of meals per day, changes in consumption of various foods, use of nutritional supplements, etc.) and changes in lifestyle habits were requested from the participations. In addition, the Healthy Nutrition Attitude Scale (ASHN) was used to determine the healthy eating attitudes of the participants. RESULTS: A total of 432 volunteers participated in the study. It was revealed that body weight increased in 38.0%of the participants and activity level decreased in 73.1%of them during the initial stage of the pandemic. Nevertheless, 44.7%of participants reported increased sleep time, 77.8%reported increased social media use, and 66.7%reported increased stress and anxiety. It was found that the most commonly used nutritional supplements during this period were vitamin C, vitamin D and multivitamin complex. Women have significantly higher ASHN scores compared to men (p < 0.001). The total ASHN scores of those whose body weight did not change and those who increased their activity level were found to be significantly higher. It was determined that as the age and education level increased, the healthy eating attitude increased. CONCLUSION: In this study, findings regarding the negative effects of the Covid 19 quarantine on the nutrition and lifestyle of the Turkish people are presented. However, those with a positive attitude toward healthy eating were observed to have better weight control and eating habits and stress management during the pandemic. Therefore, it is thought that the dissemination of healthy eating attitudes in society may contribute to the maintenance of physical and mental health in the event of a pandemic.
YETİŞKİNLERDE BESLENME OKURYAZARLIĞIN SAĞLIKLI BESLENMEYE İLİŞKİN TUTUMLAR VE BEDEN KÜTLE İNDEKSİ İLE İLİŞKİSİ ÖZ Bu çalışmada yetişkinlerde beslenme okuryazarlığı düzeyini tespit etmek ve bunun, sağlıklı beslenmeye ilişkin tutumlar ve Beden Kütle İndeksi (BKİ) ile ilişkisinin araştırılması amaçlanmıştır. Kesitsel ve tanımlayıcı nitelikte olan bu çalışmaya Türkiye'de yaşayan 20-65 yaş arası 750 gönüllü dahil edilmiştir. Veri toplama aracı olarak; Sosyodemografik bilgi formu, Yetişkinlerde Beslenme Okuryazarlığı Değerlendirme Aracı (YBOYDA) ve Sağlıklı Beslenmeye ilişkin Tutum Ölçeği (SBİTÖ) kullanılmıştır. Katılımcıların ortalama yaşı 27.10±8.70 yıl ve BKİ 23.45±4.59 kg/m 2 olup erkeklerin BKİ, kadınların değerinden daha yüksektir (sırasıyla; 26.11±3.80 kg/m 2 ve 22.67±4.52 kg/m 2 ). Katılımcıların %67.3'ünün yüksek derecede sağlıklı beslenmeye ilişkin tutuma sahip oldukları ve beslenme okuryazarlığı yönünden %83.7'sinin yeterli düzeyde, %16,3'sinin sınırda beslenme okuryazarlığının olduğu bulunmuştur. Zayıf ve ideal kilolu bireylerin okuryazarlık düzeyleri daha yüksektir. Beslenme okuryazarlığının sağlıklı beslenme tutumu ve BKİ'ni olumlu yönde etkilediği sonucuna varılmıştır.
Ozenoglu A, Balci H, Ugurlu S, Caglar E, Uzun H, Sarkis C et al. The relationships of leptin, adiponectin levels and paraoxonase activity with metabolic and cardiovascular risk factors in females treated with psychiatric drugs. Clinics. 2008; 63(5):651-60. OBJECTIVES:The aim of this study was to investigate serum leptin, adiponectin and paraoxonase1 levels in adult females receiving pharmacotherapy for various psychiatric disorders. METHODS:The study group consisted of 32 obese females (mean age 40.53 ± 11.00 years, mean body mass index 35.44 ± 5.33 kg/m 2 ) who were receiving treatment for psychiatric disorders, and the control group included 22 obese females (mean age 35.95 ± 9.16 years, mean body mass index 30.78 ± 3.33 kg/m 2 ) who were free of psychiatric disorders. Analyses were performed using a bioelectrical impedance device. Fasting blood samples were obtained for complete blood count and various biochemical tests, including determination of leptin, adiponectin and paraoxonase1 activity. RESULTS: Body mass index, waist and hip circumference, body fat percentage, fasting blood glucose, insulin, glycosylated hemoglobin, homeostasis model assesment of insulin resistance, alanine transaminase, aspartate tarnsaminase, and leptin levels were significantly higher in the study group than in controls. Although body weight was positively correlated with leptin levels in both groups, body weight was negatively correlated with adiponectin levels in the control group and positively correlated with adiponectin levels in the study group. In the study group, body mass index and hip circumference correlated positively with leptin levels, hip circumference correlated positively with adiponectin levels, and waist to hip ratio correlated positively with paraoxonase levels. In the control group, body mass index as well as waist and hip circumferences were positively correlated with leptin levels. Weight, body mass index, and hip circumference were also negatively correlated with the adiponectin/leptin ratio in the control group. CONCLUSION: This study indicates a higher risk for obesity-related disorders, particularly metabolic syndrome, diabetes and cardiovascular disease, in patients treated with psychiatric drugs.
Tüketilen besinler vücudun metabolik enerji gereksinimini sağlamakla birlikte zihin ve bilişin de dahil olduğu birçok beyin fonksiyonlarını etkilerler. Besinler ve beslenmenin duygu durumu ve davranışları etkilediği hem fiziksel hem de duygusal iyilik haline katkıda bulunduğu görüşü giderek daha çok kabul görmektedir. Bundan başka, duygu durumu da bireyin ne tür besinleri tüketeceği yönündeki seçimlerini ve kararlarını etkilemektedir. Çeşitli besin ögeleri yetersizliğinin sadece bilişsel fonksiyonlarda zayıflama ve depresif ruh haline yol açmakla kalmayıp, saldırgan davranışların sergilenmesinde de etkili olduğu bilinmektedir. Beslenmenin duygudurumu, davranış ve biliş üzerine etkilerinin ortaya çıkmasında beyin-bağırsak eksenindeki sinyallerin önemi günümüzde daha iyi anlaşılmıştır. Bu yazıda duygudurumunun besinler ve beslenme ile ilişkisine yönelik bilgiler derlenmiştir.
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