Background In developing countries, 5-10% of infants suffer from failure to thrive. Adequate feeding is the most crucial factor for optimal growth in early life.Objective To assess the differences in growth velocity at 4 to 6 months of age, based on the infant feeding practices.Methods This cross-sectional study involving 4 to 6 month-old babies from 6 public health centres in Yogyakarta was performed from August to November 2016. Data on body weight, and growth velocity as they related to weight at birth were collected. Subjects were divided into groups according to their feeding practices.Results Of 173 subjects, 130 (75%) infants were exclusively breastfed, 19 infants (11%) were given breast milk and formula, 14 (8%) infants were given breast milk and complementary food (8%), and 10 (6%) infants were given formula and complementary food. The mean growth velocity z-scores by group were as follows: exclusively breastfed 0.04 (SD 1.15) (95%CI -0.16 to 0.24), breast milk and formula -0.61 (SD 0.84) (95%CI -1.01 to -0.21), breast milk and complementary food -0.69 (SD 1.14) (95%CI -1.35 to -0.04), formula and complementary food 0.23 (SD 1.50) (95%CI: -0.84 to 1.31). The mean difference in growth velocity between the exclusively breastfed vs. breast milk and formula groups was 0.65 (SD 0.28) (95%CI: 0.10 to 1.20; P=0.02); vs. breast milk and complementary food was 0.73 (SD 0.32) (95%CI: 0.10 to 1.37; P=0.02); and vs. formula and complementary food was -0.19 (SD 0.37) (95%CI: -0.93 to 0.55; P=0.61).Conclusion Exclusively breastfed have the most optimal growth velocity compared to infants who experience other feeding practices.
Acknowledgements:We would like to thank the WHO SEARO office which provide funding for neonatal-perinatal database collection. AbstractIntroduction: Hypoglycemia leads to brain developmental
Latar belakang.Angka kematian bayi (AKB) menurut Survei Demografi dan Kesehatan Indonesia (SDKI) pada tahun 2002-2003 adalah 35 per 1000 kelahiran hidup. Dua pertiga kematian bayi merupakan kematian neonatal dan disebabkan terutama oleh persalinan prematur. Penyakit membran hialin (PMH) merupakan penyebab terbanyak dari angka kesakitan dan kematian pada bayi prematur. Tujuan.Mengetahui faktor-faktor risiko yang memengaruhi kematian pasien PMH yang dirawat di Instalasi Maternal Perinatal RSUP Dr. Sardjito.Metode. Rancangan penelitian yang digunakan adalah kasus-kontrol berdasarkan data sekunder dari data dasar neonatus dan catatan medik pasien bayi baru lahir yang dirawat dan didiagnosis PMH di RSUP Dr.Sardjito, Yogyakarta selama tahun 2007 – 2011.Hasil. Proporsi kematian neonatus dengan penyakit membran hialin di RSUP Dr. Sardjito selama 2007 – Oktober 2011 adalah 52%. Faktor risiko kematian neonatus dengan penyakit membran hialin yang bermakna secara statistik adalah asfiksia dengan OR 4,97 (IK 95% 2,39-10,28). Analisis dengan metode regresi logistik menunjukkan bahwa asfiksia merupakan faktor risiko independen kematian neonatus dengan penyakit membran hialin (aOR 5,15, IK 95% 2,43-10,91). Kesimpulan.Asfiksia merupakan faktor risiko independen kematian neonatus dengan penyakit membran hialin. Penanganan asfiksia dengan resusitasi yang tepat diperlukan untuk menurunkan risiko kematian neonatus dengan penyakit membran hialin. S
Background: Interactions between the genome and intrauterine environment can affect bone mineralization in newborns and even in adult life. Several studies show that intrauterine fetal bone mineralization or early postnatal bone condition influences the risk of osteoporosis in later life.Objectives: To determine whole body bone mineral content (WB BMC) and factors that influence neonatal WB BMC in Indonesian term newborns.Subjects/Methods: A cross-sectional study was conducted in Dr. Sardjito General Hospital, Yogyakarta, Indonesia. A total of 45 term, appropriate for gestational age (AGA) newborns were included in this study. BMC was assessed by dual-energy x-ray absorptiometry (DXA) in the first week of life. Weight (g), length (cm) and head circumference (cm) were measured at birth. Data on maternal characteristics were obtained from the maternal health records or reported by the mothers.Results: WB BMC measured in the present study (mean ± SD: 33.2 ± 9.3 g) was lower than WB BMC of similar populations in developed countries. Multiple linear regression showed that birth weight, birth length, and gestational age had a positive association with WB BMC (p = 0.048, 0.017, and <0.001, respectively), while maternal cigarette exposure had a negative association with WB BMC (p = 0.012). Male infants had significantly higher of WB BMC than female (p = 0.025). These determinants contribute to 55% variability of WB BMC.Conclusions: WB BMC in Indonesian term newborns is lower than populations in developed countries. Birth weight, length, gestational age, sex, and maternal cigarette exposure during pregnancy are significantly associated with WB BMC observed in Indonesian newborns.
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