Synthesis of novel lariat ethers containing polycyclic phenols and heterocyclic aromatic compound using graphite via Mannich reaction are herein described. For this purpose N-(methoxymethyl) azacrown ether 4 was synthesized in nearly quantitative yield. The reaction of N-(methoxymethyl) azacrown ether 4 with polycyclic phenols and heterocyclic aromatic compound was performed in 10-20 min in the presence of graphite. The graphite powder can be reused up to five times after simple washing with acetone.

We describe the synthesis of some new hydroxythioxanthones by treatment of thiosalicylic acid (TSA) with various substituted phenols in the presence of Al 2 O 3-CH 3 SO 3 H (AMA). Most of the reactions show high regioselectivity and produce thioxanthones in good yields.

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