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Nowadays supply chain (SC) evaluation is one of the critical problems in most of industries. Various frameworks and systems have been proposed to tackle the problem. In this paper, the literature of approaches, techniques and criteria for SC performance evaluation are reviewed. For this reason, related works appeared in the international journals from 1998 to 2010 are gathered and analyzed. The paper attempts to response the following four questions: (I) Which SC approaches were prevalently applied? (II) Which techniques were used to facilitate the performance measurement? (III) Which evaluation criteria were paid more attention? The result of this review is contributed in recommendation of some possible future work. The other objective of this research is to aid the researchers and practitioners in applying the approaches, techniques and criteria effectively.

N-dealkylation, the removal of an N-alkyl group from an amine, is an important chemical transformation which provides routes for the synthesis of a wide range of pharmaceuticals, agrochemicals, bulk and fine chemicals. N-dealkylation of amines is also an important in vivo metabolic pathway in the metabolism of xenobiotics. Identification and synthesis of drug metabolites such as N-dealkylated metabolites are necessary throughout all phases of drug development studies. In this review, different approaches for the N-dealkylation of amines including chemical, catalytic, electrochemical, photochemical and enzymatic methods will be discussed.

A practical, efficient, and selective electrochemical N-demethylation method of tropane alkaloids to their nortropane derivatives is described. Nortropanes, such as noratropine and norscopolamine, are important intermediates for the semi-synthesis of...

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