Este trabalho procura demonstrar como a Inova-Unicamp -Agência de Inovação da UNICAMP -produz e dissemina as informações tecnológicas geradas a partir dos produtos de conhecimento criados na Universidade e que proporcionam as condições para a inovação, e em que medida se pode considerá-la como um modelo a ser implementado em contextos similares. P P P P Palavras alavras alavras alavras alavras-----chave: chave: chave: chave: chave: informação tecnológica; inovação; produção e disseminação de informação tecnológica.
A B S T R A C TThis work aims to demonstrate how Inova-Unicamp -Agency for Innovation of UNICAMP -produces and disseminates the technological information generated from the knowledge products created at the University and which provide conditions for the innovation, and whether we can consider it as a model to be implemented in similar contexts.
Diffuse large B-cell lymphoma (DLBCL) is the most frequent type of non-Hodgkin´s lymphoma found in oral and maxillofacial regions. A large number of cases may be biologically heterogeneous, which are commonly defined as DLBCL, not otherwise specified (NOS) by the World Health Organization (WHO-2008). The present case reports on an ulcer of raised and irregular edges, found on the border between the hard and soft palate, as the first and only manifestation of an extranodal non-Hodgkin lymphoma in an 85-year-old patient. Incisional biopsy was carried out, and the specimen revealed a proliferation of large lymphoid cells suggestive of diffuse large cell lymphoma. An immunohistochemical analysis was performed. EBV-RNA was assessed by in situ hybridization that also proved to be negative. Immunohistochemical and EBV analyses are important to avoid delays and inappropriate treatment strategies. Although advanced age is considered an adverse prognostic factor, early diagnosis did prove to be a key contributory factor in the cure of non-Hodgkin lymphoma.
Key words:Diffuse large B-cell lymphoma, elderly, EBV.
The diagnosis of cervical mass is a challenge due to the wide variety of benign and malignant etiologies. Extrapulmonary small cell carcinomas (EPSCC) are rare entities, and those tumours arising as a primary cervical, especially in the thyroid gland, are exceedingly rare. As others small cell neuroendocrine carcinomas, the disease has an aggressive behavior. This case report is about a 40-years-old female patient admitted to the Hospital Felício Rocho, with airway compression caused by a cervical mass originated in the thyroid gland. The data were extracted from the medical records and information provided by the attendants. We describe here the multidisciplinary approach used to treat the patient as well as her outcome. We also review the clinical and molecular aspects of this rare entity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.