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Antibiotic use during pregnancy may increase the risk for asthma in children. We performed a meta-analysis assessing prenatal antibiotic exposure and the risk for childhood wheeze or asthma, as well as for diseases associated with the atopic march.A systematic literature search protocol (PROSPERO-ID: CRD42020191940) was registered and searches were completed using Medline, Proquest, Embase, and the Cochrane central register of controlled trials. Screening for inclusion criteria: published in English, German, French, Dutch, or Arabic, intervention (use of any antibiotic at any time point during pregnancy), and disease (reporting atopic disease incidence in children with a primary outcome of asthma or wheeze), and exclusion criteria: reviews, preclinical data, and descriptive studies, yielded 27 studies. Study quality was assessed using the Newcastle-Ottawa Assessment Scale. Quality of the evidence was assessed using the Grading of Recommendations Assessment, Development, 42

In addition to current treatment, patients who sleep on their side or face down might see a reduction in dry eye and MGD if they change their sleep pattern to the supine position.

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In teacher education, case-based learning is an efficient method to foster pre-service teachers’ diagnostic competence. To adaptively utilize text-based cases, knowledge about the effect of text characteristics is needed, but still scarce. The present study focuses on the effects of two text characteristics – text style and text subject – and on the effect of empathy on the accuracy of case-based cognitive models. This was examined with an experimental design, in which 391 pre-service teachers read a case in either psycho-narrative or externally focalized style (text style) about test anxiety or dyscalculia (text subject). Afterwards, state-empathy was measured by self-report and cognitive models were assessed with a recognition and verification test. Regression analyses showed no main effects of text characteristics, but moderation effects for text style and affective state-empathy. Implications are drawn for adaptively designing text-based cases and for possible mechanisms of how empathy is involved in diagnostic judgement formation.