Improved maternal and fetal outcome in women with SLE has occurred following integrated multidisciplinary approach. This emphasizes the importance of postponing pregnancy when predictors of poor outcome are encountered.

No abstract

Objectives: To assess the effectiveness, safety and acceptability of intracervical foley catheter and vaginal misoprostol versus vaginal misoprostol for termination of second trimester pregnancy. Methods:This clinical study was conducted on 200 pregnant patients intended for termination of pregnancy between 13-24 gestational weeks for any indication. Enrolled women were equally allocated into two groups:Group I (Misoprostol group): a standard regimen of moistened misoprostol tablets (400 μg) 4 hourly inserted vaginally. Group II (Combined group):intracervical Foley catheter inserted with a standard regimen of moistened misoprostol tablets (400 μg) 4 hourly intravaginally was used.Procedure efficacy (defined as complete abortion performed on site), safety and acceptability were assessed. Results:The induction to abortion interval was 8.16 ± 1.52 hours in the combined group compared to 12.76 ± 1.63 hours in the misoprostol group (P value<0.001) with success rate of 96% in the combined group and no major complications reported. Conclusions:Combined use of intracervical foley catheter and vaginal misoprostol is a novel safe, effective and acceptable method for termination of second trimester pregnancy. Synopsis: Combined use of intracervical foley catheter and vaginal misoprostol is a novel safe, effective and acceptable method for termination of second trimester pregnancy.

No abstract

No abstract

No abstract

Objective: to test the hypothesis whether uterine artery pulsatility index (PI) and resistance index (RI) at 6 weeks postpartum could predict amenorrhea in women wishing to use the lactational amenorrhea method (LAM) for contraception.Methods: This prospective observational study included 840 lactating women with exclusive breastfeeding who were underwent uterine artery Doppler study at 6 weeks postpartum and followed for 6 months for the return of menstruation with women divided into two groups; the amenorrhea group (n=384) and the menstruating group (n=456). The primary outcome measure was the value of uterine artery PI and RI in the prediction of amenorrhea. Data was collected and tabulated.Results: There was a highly significant difference between the two groups regarding the uterine artery PI and RI at 6 weeks postpartum (p<0.001). Uterine artery PI at a cut off value of ≥3.5 (area under the curve; AUC .846, sensitivity 92% and specificity 84.4%) and uterine artery RI at a cut off value ≥0.8 (AUC .806, sensitivity 80% and specificity 82.2%) are predictors of amenorrhea among women desiring to use the LAM by multiple logistic regression analysis. Conclusion:Uterine artery Doppler studies is simple, non-invasive and could be a valuable tool to predict amenorrhea among women desiring postpartum contraception who are interested in the LAM. Larger studies are warranted to confirm our findings.

LNG-IUS and DMPA induce hemodynamic changes in the uterine arteries denoting positive correlation with menstrual irregularities. Larger multicentre studies are warranted to potentiate our findings.