Digital subtraction angiography (DSA) is the gold standard investigation to assess the extracranial stenosis of carotid vessels. But this is an invasive diagnostic tool. So it is still a controversial issue whether duplex ultrasound is an alternative to DSA for measurement of stenosis of carotid vessels. This prospective crossectional observational study was conducted in the department of Neurology, BSMMU, Dhaka from May 2012 to April 2013 to assess the diagnostic accuracy of duplex ultrasound and its potential to replace DSA before performing carotid endarterectomy (CEA) and carotid stenting. Total of 38 patients, 33 patients of nondisabling ischaemic stroke and 5 patients with history of TIAs whose extracranial carotid stenosis was >50% on duplex ultrasound were selected for DSA. DSA was done on these vessels and stenosis was measured using NASCET criteria. Results of USD and DSA were compared to determine the sensitivity, specificity and accuracy of duplex ultrasound (USD). At 70% stenosis of right internal carotid artery and left internal carotid artery the sensitivity, specificity and accuracy were 93.8%, 63.7%, 89.5% and 93.3%, 75%, 89.5% respectively. This level of diagnostic efficiency of USD is less than that of DSA of carotid arteries. It was found in this study that, USD underestimates or overestimates the degree of carotid stenosis. DSA was safe and effective in determining stenosis in this study & there was no 67 complication. So before taking any decision for carotid endarterectomy or carotid artery stenting, digital subtraction angiography of carotid vessels should be done. DOI: http://dx.doi.org/10.3329/bmj.v43i2.21385 Bangladesh Med J. 2014 May; 43 (2): 67-71
Parkinson's disease is a common disease of old age, whose major symptoms are of motor nature. Apart from the symptoms related to motor activity, patients of PD also experience various other fluctuating symptoms of a non-motor nature. These non-motor fluctuations (NMF) have been classified according to their characteristics into three categories; dysautonomic, mental (cognitive / psychiatric), and sensory / pain. These non-motor fluctuations may have a varied presentation and unless recognized by the physicians to be a feature of PD itself, lead to unnecessary and often costly or harmful investigations. The varied presentations of the nonmotor fluctuations in patients of PD are presented in this study. patients of PD from the Movement Disorder Clinic of the Neurology
Bangladesh Journal of Neuroscience 2012; Vol. 28 (1): 52-58
Background and objectives: Migraine is now ranked as number 19 among all diseases causing disability by WHO1 which is characterized by recurrent attacks of various combinations of headache and neurological, gastrointestinal and autonomic symptoms2 accompanied by photophobia, phonophobia and vomiting3. The treatment of migraine involves acute, preventive drugs and non-pharmacological strategies. The basic principle in management of migraine is avoiding the trigger factors, blocking the mediators and splinting the end organ4. Though there is no significant curable treatment but there are some internationally proven and well accepted prophylactic medication which reduces headache severity, frequency, duration and risk for rebound5. Sodium valproate and pizotifen are commonest of them6, where sodium valproate is more effective than pizotifen in the prophylaxis of migraine patients. Methods: This study was a single blind randomized clinical trial carried out in the neurology outpatient department of Bangabandhu Sheikh Mujib Medical University, Dhaka (BSMMU) for the period of 2 years, among adult patients between the age of 16-50 years. Results: A total of 120 patients were included & divided into two groups such as group-A(60 patients) treated by sodium valproate & group-B(60 patients) treated by pizotifen for a period of 6 months and followed up every two months for 3 times and showed sodium valproate is more effective than pizotifen. Conclusion: This study permit to conclude that efficacy of sodium valproate is more than pizotifen in the prophylaxis of migraine patients. DOI: http://dx.doi.org/10.3329/bjn.v28i2.17174 Bangladesh Journal of Neuroscience 2012; Vol. 28 (2): 81-87
A 40 years old man presented with progressive weakness and distal paraesthesia of limbs with difficulty in walking for last seven years. As the patient was not investigated thoroughly, a diagnostic dilemma was persisted. This patient went abroad & investigated thoroughly and yet not reached to a confirm diagnosis. Subsequently this patient reported to us and diagnosed it to be a case of Idiopathic Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) responded to oral steroid therapy. After follow-up, this patient showed marked improvement. So diagnostic dilemma that persisted with such a patient that showed improvement with treatment and a challenge to a treatable condition had encouraged us to report the case. DOI: http://dx.doi.org/10.3329/bjn.v28i2.17185 Bangladesh Journal of Neuroscience 2012; Vol. 28 (2): 132-140
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.