Pattern of Non-Motor Fluctuations in Patients of Parkinson’s Disease

Abstract

Parkinson's disease is a common disease of old age, whose major symptoms are of motor nature. Apart from the symptoms related to motor activity, patients of PD also experience various other fluctuating symptoms of a non-motor nature. These non-motor fluctuations (NMF) have been classified according to their characteristics into three categories; dysautonomic, mental (cognitive / psychiatric), and sensory / pain. These non-motor fluctuations may have a varied presentation and unless recognized by the physicians to be a feature of PD itself, lead to unnecessary and often costly or harmful investigations. The varied presentations of the nonmotor fluctuations in patients of PD are presented in this study. patients of PD from the Movement Disorder Clinic of the Neurology

Clinical approach to nonmotor sensory fluctuations in Parkinson's disease

“…Ali et al [12] investigated NMFs in 128 PD patients in an outpatient Movement Disorders Clinic. An unspecified structured questionnaire was administered that included sensory (6 items), autonomic (16 items), and psychiatric symptoms (6 items).…”