The global demand for good quality food is going to be increased gradually. Mushrooms are broadly used as healthy nutritious meals. The nutritional values of extracts from four distinct Pleurotus species—Pleurotus ostreatus, Pleurotus sajor-caju, Pleurotus sapidus, and Pleurotus columbinus—were determined in the current study. Firstly, proximate analysis of selected Pleurotus species was performed followed by the Bradford assay to analyze the protein spectrophotometrically; high-performance liquid chromatography (HPLC) was performed for sugar determination while GC-MS was done to determine fatty acids on organic extracts of selected mushrooms. Descriptive statistics were used to calculate the percentages while significance was determined by SPSS statistics. The results depicted that fat, protein, ash, fiber, energy contents, and total carbohydrate were in the range of 0.64-2.02%, 16.07-25.15%, 2.1-9.14%, 6.21-54.12%, 342.20-394.30 kcal/100 g, and 65.66-82.47%, respectively. The protein’s maximum concentration was observed in P. ostreatus followed by P. columbinus>P. sajor-caju>P. sapidus, sequentially. Various sugars may or may not be present in selected Pleurotus spps. Among the fatty acids, the prevalence of UFA was more than that of saturated fatty acids among all selected mushrooms. From this study, it is concluded that all four Pleurotus spps. have excellent nutritional composition and can be used as valuable food and a great source of biochemical compounds.
<p>Rapid emergence and spread of current pandemic of COVID-19 has evoked the medical science community to investigate quick, accurate and reliable diagnostic and prognostic approaches. Early identification of causative agent SARS-CoV-2 in host and monitoring the blood biochemical parameters for the assessment of disease severity leads to devise proper management and care to minimize mortality rate. The research studies on biochemical markers in COVID-19 published till May 15, 2020, are retrieved by using keywords “biochemical markers, biomarkers, COVID-19, and SARS-CoV-2” at web search engines (Google scholar & PubMed). Selected articles are reviewed for the selected biomarkers that can be useful prognosticators of mild and severe patient outcomes to provide assistance in clinical management of the outbreak for frontline medical personnel. Biochemical tests include panels of liver and renal functioning, lactate dehydrogenase, C-reactive protein, and interleukin-6 that have abnormal and deteriorated values as compared to normal controls and mild cases. Patients having baseline comorbidities such as hepatitis or chronic kidney disorder might develop multiorgan injuries during hospitalization but in other patients’ biomarkers measure the status of inflammatory response and drug therapy outcomes</p>
: Cardiovascular diseases (CVD), primarily inflammatory cardiomyopathy, are characterized by the infiltration of inflammatory cells into the myocardium. It has a relatively high risk of deteriorating heart function and has heterogeneous etiologies. Inflammatory cardiomyopathy is mainly mediated by viral infections but can also be mediated by protozoa, fungal or bacterial infections. Besides that, there are a wide variety of drugs, toxic substances, and systemic immune-mediated diseases that result in the development of cardiovascular diseases (CVDs). Despite broad research, inflammatory cardiomyopathy has a poor prognosis. The roles of the pathogens, host genomic counterparts and environmental triggers in the progression of disease are still under consideration, including the role of some viruses as active inducers and others as bystanders. In this review article, we review the available evidence on the types, pathogenesis and treatment of myocarditis, inflammatory cardiomyopathy, and atherosclerosis with a particular focus on virus-associated cardiac diseases.
Introduction: Breast-cancer-related morbidity and mortality can be reduced by following worldwide-accepted screening guidelines and by appropriate education and training of health professionals on risk identification and screening. The study aimed to determine the significance of educational sessions in improving health professionals’ knowledge about breast cancer, particularly screening modalities that can benefit the patients. Method and Materials: An interventional study was conducted among 260 health professionals, including medical students, nurses, and allied health professionals. The intervention was an educational session on breast cancer risks and screening guidelines. Health professionals’ knowledge about breast cancer risk, presentation, and screening were tested by a structured questionnaire before and after the educational session. Data were analyzed using Statistical Package for the Social Sciences 26. Chi-square was used to identify differences in pre and post-test. P value was considered significant at <0.05. Results: There is a significant difference between pre-session and post-session responses in all areas of knowledge about breast cancer, with much improved outcomes after the educational session. Conclusion: Health professionals lack knowledge about breast cancer risk factors, screening tools, presentation, and management. Regular education sessions improve these knowledge gaps and help early detection and treatment of women at risk of breast cancer.
Human cheek epithelial cells, despite residing in an almost neutral environment of the mouth, are exposed to many acidic stimuli, so these cells may possess acid resistance. Our research's objective is to find out if isolated human cheek epithelial cells can survive in highly acidic conditions, and whether there is any difference in acid resistance between cheek epithelial cells of males and females; and to establish a protocol. We collected 3 buccal swab samples from each male or female participant and gave following 3 different treatments to their samples: (ⅰ) Milli-Q water (ⅱ) HCl with pH of -0.48 (ⅲ) HCl with pH of -0.48 and, then, rehydration with Milli-Q water. Staining and microscopic analysis showed that cheek epithelial cells did not burst after acid treatment. However, they slightly shrunk in size and were stained substantially darker. Moreover, cells that were rehydrated after acid treatment, provided further evidence of their survival because these cells, as a result of rehydration, had substantially regained bigger size as well as lighter staining. Furthermore, at pH of -0.48, no difference was observed in acid resistance of the cells from the two genders. Results of this study, which is the only one to incubate cheek epithelial cells at pH < 2.0, manifest that the human cheek epithelial cells, isolated from any of the two genders, are extremely acid-resistant and do not burst in highly acidic conditions. Besides, these cells may also be useful as model cells for the study of acid-resistant pathogens and acid-resistant cancer cells.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.