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In this small group of patients with schizophrenia, no deterioration in clinical status in several domains was noted after changing from branded to generic clozapine. This finding is consistent with pharmacologic data suggesting bioequivalence of the 2 products. Results, however, must be interpreted cautiously due to the lack of optimal study controls and small sample size.

The article reports the case of a 39-year-old male who was diagnosed with and treated for bipolar disorder. Over the past 18 months, the patient has experienced new onset of auditory hallucinations and worsening of his psychotic symptoms. The treating psychiatrists changed the diagnosis from bipolar disorder to schizoaffective disorder. The authors discuss hierarchical and nonhierarchical approaches to psychiatric diagnosis in relation to this case report. (Journal of Psychiatric Practice 2003;9:324-327)

Token economies are an effective way of changing various behaviors including acquiring new skills, reducing undesired behaviors, reducing aggression, increasing treatment compliance, and improving psychiatric unit management. This study examines the long‐term effect of a token economy on an acute care, inpatient psychiatric unit. The two years following the implementation of a unit based token economy are compared with the 12 months prior to implementation. The results show a significant reduction in total assaults as well as fewer staff injuries resulting in loss of time from work. Copyright © 2003 John Wiley & Sons, Ltd.

Linear discriminant analysis was used to construct a series of discriminant functions including subsets of demographic variables and Mini-Mental State Examination item responses for a case series and a population sample. A 9-item discriminant function including the variables for time orientation, recall, calculation, copying a figure, age, writing, 3-step command, naming, and race distinguished demented subjects from community controls with 91% sensitivity and 88% specificity. The same discriminant function classified Alzheimer's disease patients and controls with 96% sensitivity and 98% specificity. This discriminant function has been cross-validated as a potential screening instrument for Alzheimer's disease in a community-based sample.

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