<b><i>Background:</i></b> Burn hemangioma, also known as scalded pyogenic granuloma, is considered a variant of pyogenic granuloma, but unlike the classic type it presents with rapid progression. Most patients are infants and young children with a history of burns caused by liquids. <b><i>Objective:</i></b> The present study aims to present all patients with burn hemangiomas treated at our institutions with a full clinical and histopathological assessment. <b><i>Patients and Methods:</i></b> This case series includes 34 cases that were treated during the period from 2016 to 2021. <b><i>Results:</i></b> A total of 34 patients (16 female/18 male, mean age of 17.6 years) were included. Two age groups presented: infants and children (<i>n</i> = 22, age range 0.5–8 years, 10 female/12 male), and adults (<i>n</i> = 11, age range 25–44 years, 6 female/6 male). Lesions appeared 1–2 weeks following predominantly second-degree burns, and multiple lesions predominated in infants and children. The lesions evolved to large lesions within weeks, and these appeared to be either static or involute. The histopathology was compatible with hemangioma, rather than pyogenic granuloma. <b><i>Conclusion:</i></b> Burn hemangioma should be considered a new variant of hemangioma rather than a type of pyogenic granuloma that follows second-degree burns. They have many similarities with infantile hemangioma, both clinically and histopathologically.
Background: Hair graying is an aging sign that was found to be associated with several systemic diseases like ischemic heart disease, osteopenia, and autoimmune diseases. Metabolic syndrome was applied to the clustering of risk factors that often associate with increased risk for atherosclerotic cardiovascular disease. Aim of Study: Our work aimed to test retrospectively the association between onset of hair graying and risk of metabolic syndrome. Patients & Methods: Four hundred and eighty one gray hair individuals, with no history of any type of atherosclerotic disease, participated in the study. The participants were divided into two groups according to the presence or absence of criteria of metabolic syndrome into control and metabolic syndrome groups, and each individual in both groups was asked about the decade (2 nd-6 th) when he/she firstly noticed that he/she had a gray hair. A comparison was made regarding the age of onset of graying between the two groups. Results: There was a significant difference in decades between individuals with metabolic syndrome and the control group and was found in the 4 th and 5 th decade of life (P =0.045 & 0.024 respectively) while the difference was not significant in the 2 nd , 3 rd and 6 th decades of life. The mean age of onset of hair graying in metabolic syndrome was 36.207 ± 8.30 year and the control group was 38.434 ±8.31 year, there is also a significant difference between the two groups (P value=0.003). Conclusion: patients with metabolic syndrome have an earlier age of onset of gray hair.
Background: Pityriasis alba, is a common benign skin disease occurring predominantly among children, often on their face. Clinically, the spots of pityriasis alba are off-white in color, round with poorly defined margins that bear scanty fine scales on it. No specific cause of pityriasis alba has been identified . In this disease, the number of melanocytes declines and melanosomes reduce within melanocytes. Vitamin D exerts its effect via the vitamin D receptor on melanocytes, if intracellular Ca2+ level decreases, this leads to high levels of reduced thioredoxin this, in turn, inhibit tyrosinase activity with the inhibition of melanin synthesis. In addition, the apoptotic activity of melanocytes reduces by the active form of vitamin D. Aim: The study aimed to assess the status of vitamin D for patients with pityriasis alba. Materials and Methods: 44 patient diagnosed with pityriasis alba were enrolled and the second group of 44 controls was involved in our study. Serum levels of circulating 25 (OH) D were measured. Results: None of the cases had sufficient serum level; the level ranged between 8.1-27.3 ng/ml. The patients had lower circulating vitamin D levels than controls. Conclusion: Our findings in the present study are significant, but further studies with large samples are needed to correlate the extent and severity of pityriasis alba with vitamin D deficiency.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.