BACKGROUND: Diabetes mellitus is a serious disease that affects more than 340 million people and causes approximately 20% of diabetic ulcer cases worldwide. Wound healing is a complex and dynamic process in restoring cellular structures and tissue layers. It consists of four continuous overlapping phases that are precisely programmed AIM: This study aims to examine the adjuvant administration of bitter melon leaf extract to increase the healing of diabetic foot ulcers (DFU). METHODS: This study used a randomized, double-blind, and placebo-controlled trial. A total of 30 DFU patients with a perfusion, extent, depth, infection, and sensation (PEDIS) score of 1–8 who met the criteria were divided into two groups, namely, the treatment group with adjuvant administration of bitter melon leaf extract at a dose of 6 g/day as many as 15 patients and the control group 15 patients with placebo. This intervention was carried out for 4 weeks. DFU cure was measured by PEDIS scores at baseline, weeks 2, 3, and the end of week 4. Data were analyzed using paired t-test and independent t-test. RESULTS: After 4 weeks of treatment, the PEDIS score in the treatment group decreased at week 2 (0.9 ± 1.8), but not significant (p = 0.19), decreased at week 3 (1.9 ± 1.9) and significant (p = 0.01), decreased in week IV (2.3 ± 2.1) and significantly (p = 0.001). The control group experienced a decrease in week 2 (0.3 ± 2.3), but not significant (p = 0.71), decreased in week 3 (1.2 ± 2.5), but not significant (p = 0.18), decreased in week 4 (1.9 ± 2.7) and significantly (p = 0.03), and there was an effect of adjuvant administration of bitter melon leaf extract on the cure of DFU (p = 0.004). CONCLUSION: Adjuvant administration of bitter melon leaf extract has been shown to increase the healing of DFU.
This study aims to investigate the effects of slow deep breathing (SDP) and dhikr on sleep disturbance in cancer patients during chemotherapy. This study used a Quasi-experiment design. A total of 44 cancer patients experiencing chemotherapy who met the inclusion criteria were divided into 2 groups of 22 patients. The treatment group practiced SDB and dhikr, while the control group practiced normal breathing. This intervention was performed for 30 minutes and repeated for 3 cycles of chemotherapy. Furthermore, sleep disturbance is measured by the Pittsburgh Sleep Quality Index sheet. The data is analyzed using the Paired t-test, independent t-test, and Chi-square test with a significance limit of p <0.05. The result after 3 treatment cycles, sleep disturbances decreased in the treatment group from 7.64 ± 2.19 to 6.73 ± 1.78 or decreased by 0.91 ± 1.54, but in the control group, there was an increase from 5.00 ± 1 .90 to 5.18 ± 1.99 or an increase of 0.18 ± 0.85. The analysis results of SDP and dhikr effect on sleep disturbance in cancer patients during chemotherapy is significant (p=0.010). This study concludes SDB, and Dhikr can reduce sleep disturbance in cancer patients during chemotherapy.
Diabetes mellitus is a disease that can cause sufferers to experience an increase in blood glucose levels in their body. Increased blood glucose levels can be prevented by implementing self-care routinely and getting support from the family. Objective: To find out there is a relationship between the family support with glycemic status in patients with type 2 diabetes at the Banyuanyar Health Center. Methods: Using a descriptive quantitative correlation research with a cross-sectional approach. The population of this study were patients with type 2 diabetes mellitus at the Banyuanyar Health Center as many as 469 people. Sampling technique using probability sampling with simple random sampling obtained a large sample of 99 respondents. Data collection by using a questionnaire. Data analysis using Pearson Product Moment. Results: 77 respondents had sufficient family support and 68 respondents had diabetes mellitus on their glycemic status. The results of the analysis show that there is a significant relationship between family support and glycemic status where the significant value (p-value) is 0.0001 <0.05. The correlation coefficient value between family support and glycemic status is -0. There is a relationship between the family support and associated with glycemic status (p-value 0.0001). Conclusion: There is a relationship between the family support and associated with glycemic status in type 2 DM patients at the Banyuanyar Health Center.
Monitoring of glucose levels is essential in preventing the complications of diabetes mellitus, including short, medium and long-term monitoring. Short-term monitoring includes random plasma glucose, fasting plasma glucose, 2-hour post prandial plasma glucose and Oral glucose tolerance tests (OGTT). The medium-term monitoring includes fructosamine and Glycated albumin (GA) while the long-term monitoring is glycated hemoglobin (HbA1c). Currently, the most recommended examination for glucose level monitoring in patients with diabetes mellitus is the glycated hemoglobin (HbA1c). However, there seem to be some conditions where the HbA1c value is doubtful or unreliable. Some of these conditions include anemia, thalassemia, dialysis and pregnancy. The best choice at this time is GA.
Background: Diabetes Mellitus (DM) is a metabolic disorder which is marked by an increase in fasting blood glucose level caused by the demage to the function of pancreas influenced by factors of age, sex, and education. Purpose: To examine relationship between characteristics (age, sex and education) of respondent with fasting blood glucose level in patients diabetes mellitus type 2 in Purwosari public health center Surakarta. Method: This research type and design used is quantitative research, analytic observational research methods with cross sectional research approach. The sample in this research is 92 people with technique purposive sampling. Data collection using questionnaire’s characteristic responden and fasting blood glucose levels with glucometer. The study was conducted in January – February 2020 at Purwosari public health center Surakarta. Data analysis using Chi square test with signicance < 0.05. Result: The majority of respondets have hyperglicemia of 57 people with age range 65 – 79 years, female, level of education is high school. The results of this study indicate that there is a relationship of age (p value = 0,006) with fasting blood glucose; sex (p value = 0,017) with fasting blood glucose; education (p value = 0,030) with fasting blood glucose.
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