The consistent finding of reduced 'reproductive fitness' in those with non-affective psychoses needs to be incorporated in the genetic epidemiology of these disorders. Despite this reduction in fertility and fecundity, many patients with psychoses are parents. Services need to remain mindful of the special needs of these patients.

Further advances in magnetic hyperthermia might be limited by biological constraints, such as using sufficiently low frequencies and low field amplitudes to inhibit harmful eddy currents inside the patient's body. These incite the need to optimize the heating efficiency of the nanoparticles, referred to as the specific absorption rate (SAR). Among the several properties currently under research, one of particular importance is the transition from the linear to the non-linear regime that takes place as the field amplitude is increased, an aspect where the magnetic anisotropy is expected to play a fundamental role. In this paper we investigate the heating properties of cobalt ferrite and maghemite nanoparticles under the influence of a 500 kHz sinusoidal magnetic field with varying amplitude, up to 134 Oe. The particles were characterized by TEM, XRD, FMR and VSM, from which most relevant morphological, structural and magnetic properties were inferred. Both materials have similar size distributions and saturation magnetization, but strikingly different magnetic anisotropies. From magnetic hyperthermia experiments we found that, while at low fields maghemite is the best nanomaterial for hyperthermia applications, above a critical field, close to the transition from the linear to the non-linear regime, cobalt ferrite becomes more efficient. The results were also analyzed with respect to the energy conversion efficiency and compared with dynamic hysteresis simulations. Additional analysis with nickel, zinc and copper-ferrite nanoparticles of similar sizes confirmed the importance of the magnetic anisotropy and the damping factor. Further, the analysis of the characterization parameters suggested core-shell nanostructures, probably due to a surface passivation process during the nanoparticle synthesis. Finally, we discussed the effect of particle-particle interactions and its consequences, in particular regarding discrepancies between estimated parameters and expected theoretical predictions.

OBJETIVOS: Estabelecer o perfil socioeconômico, demográfico e funcional de idosos atendidos pela Estratégia Saúde da Família (ESF) em Paranoá, Distrito Federal, Brasil, e observar as possíveis associações entre os fatores encontrados com o nível de capacidade funcional desta população. MÉTODOS: Trata-se de pesquisa descritiva, com aplicação de questionário socioeconômico e demográfico, escala de Lawton e índice de Katz, para obtenção dos dados sobre funcionalidade em 93 idosos. Para a análise estatística, utilizaram-se o teste exato de Fisher e o qui-quadrado, adotando nível de significância de 0,05. RESULTADOS: Não houve associação entre os elementos de saúde (considerando a autopercepção da saúde, doenças como hipertensão arterial, diabetes, reumatismo, asma, bronquite, varizes, insônia, infarto agudo do miocárdio e acidente vascular encefálico), ou aspectos sociodemográficos e econômicos com funcionalidade, exceto para os fatores histórico de quedas e visita aos amigos (p<0,05). CONCLUSÃO: Houve manutenção principalmente das atividades básicas de vida diária, com pequeno percentual de comprometimento das atividades instrumentais de vida diária.

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Nanosized maghemite-like particles with reduced size-distribution were obtained using a one-pot synthesis route in aqueous medium. Forced hydrolysis of iron ions in ammoniac solution led to the formation of magnetite nanoparticles that were oxidized to maghemite in a hydrothermal digestion step that reduced the polydispersity of nanograins. The prepared nanoparticles were characterized by chemical analysis, X-ray diffractometry, magnetization, Raman spectroscopy and transmission electron microscopy measurements. Data showed that 14 nm-sized particles with polydispersity of about 0.14 were produced and, differently from other procedures, neither additional steps nor toxic reagents were needed to reduce size-dispersion or to oxidize magnetite to maghemite. These facts per se turn such nanodevice into a good potential choice for biomedical applications.

ABSTRACT: Objective: The aim of this study was to verify the association between types of dependence for basic and instrumental activities of daily living and the occurrence of falls in the elderly. Methods: A cross-sectional, population-based study using data from 23,815 elderly people drawn from the National Health Survey (NHS) in 2013. The NHS, conducted by the Brazilian Institute of Geography and Statistics (IBGE) and the Ministry of Health, presents data collected in 81,767 households in more than 1,600 municipalities. The association between the independent variable (ADL disabilities) and the dependent variable (history of falls) was performed through multiple and crude analyses, regression. Results: There was a greater association between using the toilet and transfers (ABVD) and falls, and between shopping and taking care of finances (IADL) and falls. In addition, the association between Basic Activities of Daily Living and falls was greater for up to four activities, and the Instrumental Activities of Daily Living for up to three activities. Conclusion: Thus, the results obtained in the NHS reinforce the planning of preventive strategies considering the functional dependence.