Migraine is a type of headache characterized by episodic throbbing or pulsating pain usually occurring in one side of the head. According to the prevalence report, it is the third most prevalent disorder worldwide. In Unani Medicine, it is called shaqiqa derived from an Arabic word ‘shaq’ meaning ‘half part’. The condition is difficult to treat by medication only. Unani system of medicine has a theory of imala (diversion of morbid matters) and tanqia-e-mawad (evacuation of morbid matters) by using different modes of ilaj bit tadbeer (regimenal therapy) and pharmacotherapy. A therapy including regimenal therapy and pharmacotherapy has been used in this case for 23 days. Nutool (irrigation therapy) and Dalak (massage therapy) by Rogan-e-Kaddu (medicated oil) were given as regimenal mode and Itrifal Ustukhuddus, Itrifal Kishnizi and Jawarish Shahi were given orally as pharmacotherapy. Signs and symptoms were assessed by Visual Analogue Scale (VAS) and result was assessed as per grading system, such as complete relief, relief, partial relief and no relief. After completion of the treatment and post treatment follow up, complete relief from the sign and symptoms was observed. The study suggested the authenticity of principles of treatment of Unani Medicine.
Dubin-Johnson syndrome is a rare inherited disorder associated with a defect in the ability of hepatocytes to secrete conjugated bilirubin into bile. Patients usually present with chronic or recurrent attacks of jaundice with conjugated hyperbilirubinemia. A dark pigment accumulates in the liver,which is responsible for itscharacteristic black color.It is a benign condition with a normal life expectancy and no specific treatment is required. We report a case of Dubin-Johnson syndrome in a 20-year-old man with recurrent episodes of jaundice, whose laboratory data revealed a mild conjugated hyperbilirubinemia, remaining liver function tests were normal and diagnosis was confirmed by the presence of dark brown pigment on microscopy of liver biopsy. BIRDEM Med J 2021; 11(3): 235-238
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