The purpose of this study was to estimate the antioxidant and anti‐inflammatory activities of methanolic extracts of date palm fruits grown in Algeria. Four in vitro methods were employed to evaluate the antioxidant activity (AA), namely β‐carotene‐linoleic acid system, phosphomolybdenum method, 2,2‐diphenyl‐1‐picrylhydrazyl radical scavenging activity and Ferric‐Reducing Antioxidant Power assay. The anti‐inflammatory activity was carried out using carrageenan‐induced edema model. The extracts were found to be a rich source of polyphenols, flavonoids and flavonols. The methanolic extract of Ali Ourached cultivar showed the highest AA for the four methods cited previously (76.85%, 90.25 μmol of ascorbic acid/g of extract, 206 µg/mL and 56.04 μmol Fe (II) ∕ 100 g DW, respectively). Anti‐inflammatory findings revealed noticeable reduction of paw volume ranging from 35.64 to 67.56% as a response to oral administration of 250 mg/kg dose of methanolic extracts. This study constitutes an endeavor for understanding the bioactive phytochemical variability in date palm fruit cultivars and corresponding antioxidant and anti‐inflammatory activities.
Practical Applications
In this study, the biological potentials of methanolic extracts of date palm fruits (Phoenix dactylifera L.) were evaluated. The date cultivars could potentially be considered as a functional food and could be useful as a good source of natural antioxidant compounds with possible applications to reduce oxidative stress and treatment of chronic inflammatory pathologies. The results suggest that date palm fruits contain potent antioxidant and anti‐inflammatory properties that can find application in food science, food technology and nutrition.
L'objectif de cette étude est de déterminer la teneur en composés phénoliques totaux de l'huile d'olive de la variété Chemlal obtenue par extraction artisanale et d'en tester leur pouvoir antioxydant. La teneur phénolique a été déterminée par la méthode universelle Folin-Ciocalteu, alors que l'activité antioxydante a été évaluée par deux méthodes complémentaires: le test du radical libre 2,2-diphenyl-1-picrylhydrazyl et le test du β-carotène/acide linoléique. Cette huile d'olive a montré une teneur en composés phénoliques totaux de 167,29 ± 2,71mg EAG/kg et une valeur d'IC 50 égale à 25, 38 ± 0,64mg/kg par le test DPPH et une activité antioxydante relative par le test β-carotène/acide linoléique de l'ordre de 67,40 ± 1,02%. Le contrôle positif hydroxy toluène butyle (BHT) a dévoilé respectivement 23,86 ± 0,14mg/kg et 95,88 ± 0,85%. Ces résultats révèlent une possible utilisation de cette huile dans la lutte contre les maladies liés au stress oxydant.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.